U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rps12 ribosomal protein S12 [ Mus musculus (house mouse) ]

Gene ID: 20042, updated on 5-Feb-2023

Summary

Go to the top of the page Help
Official Symbol
Rps12provided by MGI
Official Full Name
ribosomal protein S12provided by MGI
Primary source
MGI:MGI:98105
See related
Ensembl:ENSMUSG00000061983 AllianceGenome:MGI:98105
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in Golgi apparatus and cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit and cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 1796.8), liver E14.5 (RPKM 1660.8) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rps12 in Genome Data Viewer
Location:
10; 10 A4
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (23661081..23663281, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (23785183..23787383, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35291 Neighboring gene nuclear encoded tRNA trytophan 1 (anticodon CCA) Neighboring gene small nucleolar RNA, C/D box 100 Neighboring gene small nucleolar RNA, H/ACA box 33 Neighboring gene predicted gene, 23130 Neighboring gene solute carrier family 18, subfamily B, member 1 Neighboring gene vanin 3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cloning and sequencing of mouse ribosomal protein S12 cDNA. Ayane M, et al. Nucleic Acids Res, 1989 Aug 25. PMID 2780296, Free PMC Article
  2. Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts. Raines AM, et al. Development, 2013 Jul. PMID 23760953, Free PMC Article
  3. The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation. Chen N, et al. J Biol Chem, 2008 Jul 25. PMID 18495661, Free PMC Article
  4. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Distler U, et al. Proteomics, 2014 Nov. PMID 25211037
  5. Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Kondrashov N, et al. Cell, 2011 Apr 29. PMID 21529712, Free PMC Article

See all (32) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC102111, MGC102112, MGC102499, MGC117504

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of positive regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
40S ribosomal protein S12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001407441.1 → NP_001394370.1  40S ribosomal protein S12 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC160147
    UniProtKB/Swiss-Prot
    Q6ZWZ6
    UniProtKB/TrEMBL
    A0A6P5QJZ7

  2. NM_001407442.1 → NP_001394371.1  40S ribosomal protein S12 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC160147
    UniProtKB/Swiss-Prot
    Q6ZWZ6
    UniProtKB/TrEMBL
    A0A6P5QJZ7

  3. NM_001407443.1 → NP_001394372.1  40S ribosomal protein S12 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC160147

  4. NM_001407444.1 → NP_001394373.1  40S ribosomal protein S12 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC160147

  5. NM_011295.7 → NP_035425.2  40S ribosomal protein S12 isoform a

    See identical proteins and their annotated locations for NP_035425.2

    Status: VALIDATED

    Source sequence(s)
    AC160147
    Consensus CDS
    CCDS23733.1
    UniProtKB/Swiss-Prot
    Q6ZWZ6
    UniProtKB/TrEMBL
    A0A6P5QJZ7, Q6ZWZ6
    Related
    ENSMUSP00000151305.2, ENSMUST00000218107.2
    Conserved Domains (1) summary
    pfam01248
    Location:16 → 111
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    23661081..23663281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244962.1 → XP_030100822.1  40S ribosomal protein S12 isoform X1

RNA

  1. XR_003948630.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P63323.3 GenPept UniProtKB/Swiss-Prot:P63323

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous