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CDCP2 CUB domain containing protein 2 [ Homo sapiens (human) ]

Gene ID: 200008, updated on 11-Jun-2021

Summary

Official Symbol
CDCP2provided by HGNC
Official Full Name
CUB domain containing protein 2provided by HGNC
Primary source
HGNC:HGNC:27297
See related
Ensembl:ENSG00000157211 MIM:612320
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CDCP2 in Genome Data Viewer
Location:
1p32.3
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (54132687..54153181, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (54598360..54618854, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A N-terminal and central domain containing 2 Neighboring gene microRNA 4781 Neighboring gene cytochrome c oxidase subunit 7B pseudogene Neighboring gene cytochrome b5 reductase like Neighboring gene mitochondrial ribosomal protein L37 Neighboring gene single stranded DNA binding protein 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
CUB domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353655.3NP_001340584.1  CUB domain-containing protein 2 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL357673
    Consensus CDS
    CCDS85977.1
    Related
    ENSP00000489959.1, ENST00000530059.2
    Conserved Domains (3) summary
    cd00041
    Location:30141
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:257370
    CUB; CUB domain
    cl27758
    Location:380463
    Zona_pellucida; Zona pellucida-like domain
  2. NM_201546.5NP_963840.2  CUB domain-containing protein 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_963840.2

    Status: VALIDATED

    Source sequence(s)
    AL357673
    Consensus CDS
    CCDS588.2
    UniProtKB/Swiss-Prot
    Q5VXM1
    Related
    ENSP00000360381.1, ENST00000371330.1
    Conserved Domains (2) summary
    cd00041
    Location:30141
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:257370
    CUB; CUB domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    54132687..54153181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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