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Rpl28 ribosomal protein L28 [ Mus musculus (house mouse) ]

Gene ID: 19943, updated on 2-Nov-2024

Summary

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Official Symbol
Rpl28provided by MGI
Official Full Name
ribosomal protein L28provided by MGI
Primary source
MGI:MGI:101839
See related
Ensembl:ENSMUSG00000030432 AllianceGenome:MGI:101839
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D7Wsu21e
Summary
A structural constituent of ribosome. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several structures, including extraembryonic component; gonad; intestine; liver; and lung. Orthologous to human RPL28 (ribosomal protein L28). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bladder adult (RPKM 268.3), liver E14.5 (RPKM 253.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rpl28 in Genome Data Viewer
Location:
7 A1; 7 2.77 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4795964..4797546)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4792965..4794547)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene interleukin 11 Neighboring gene transmembrane protein 190 Neighboring gene transmembrane protein 238 Neighboring gene STARR-positive B cell enhancer ABC_E6507 Neighboring gene predicted gene, 57780 Neighboring gene STARR-positive B cell enhancer ABC_E441 Neighboring gene ubiquitin-conjugating enzyme E2S Neighboring gene STARR-seq mESC enhancer starr_17941 Neighboring gene shisa family member 7 Neighboring gene predicted gene, 36127

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Sequence and expression of a cDNA encoding the mouse homologue of the rat ribosomal protein L28. Burke PS, et al. Gene, 1994 May 16. PMID 7515017
  2. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Ito M, et al. Mol Cell, 2000 Apr. PMID 10882104
  3. Degradation of NLRP3 by p62-dependent-autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia. Zhang D, et al. CNS Neurosci Ther, 2023 Oct. PMID 37072933, Free PMC Article
  4. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Kubagawa H, et al. Proc Natl Acad Sci U S A, 1997 May 13. PMID 9144225, Free PMC Article
  5. Drp1 regulates transcription of ribosomal protein genes in embryonic hearts. Zhao Q, et al. J Cell Sci, 2022 Feb 15. PMID 35099001, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC107666, MGC115078

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cell body IEA
Inferred from Electronic Annotation
more info
  
located_in cell body ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in dendrite IEA
Inferred from Electronic Annotation
more info
  
located_in dendrite ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
large ribosomal subunit protein eL28
Names
60S ribosomal protein L28
NP_033107.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009081.2 → NP_033107.1  large ribosomal subunit protein eL28

    See identical proteins and their annotated locations for NP_033107.1

    Status: PROVISIONAL

    Source sequence(s)
    AK012368
    Consensus CDS
    CCDS39742.1
    UniProtKB/Swiss-Prot
    P41105
    UniProtKB/TrEMBL
    Q5M9J8, Q5M9N5
    Related
    ENSMUSP00000032597.6, ENSMUST00000032597.12
    Conserved Domains (1) summary
    pfam01778
    Location:5 → 119
    Ribosomal_L28e; Ribosomal L28e protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    4795964..4797546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41105.2 GenPept UniProtKB/Swiss-Prot:P41105

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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