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Rpl19 ribosomal protein L19 [ Mus musculus (house mouse) ]

Gene ID: 19921, updated on 9-Sep-2018

Summary

Official Symbol
Rpl19provided by MGI
Official Full Name
ribosomal protein L19provided by MGI
Primary source
MGI:MGI:98020
See related
Ensembl:ENSMUSG00000017404 Vega:OTTMUSG00000002909
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in CNS E11.5 (RPKM 435.4), placenta adult (RPKM 390.2) and 28 other tissues See more
Orthologs

Genomic context

See Rpl19 in Genome Data Viewer
Location:
11; 11 D
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (98023080..98030493)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (97888024..97891807)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 5C Neighboring gene calcium channel, voltage-dependent, beta 1 subunit Neighboring gene SH3 and cysteine rich domain 2 Neighboring gene F-box and leucine-rich repeat protein 20

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
5.8S rRNA binding ISO
Inferred from Sequence Orthology
more info
 
large ribosomal subunit rRNA binding ISO
Inferred from Sequence Orthology
more info
 
structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of ribosome IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
 
translation IC
Inferred by Curator
more info
PubMed 
Component Evidence Code Pubs
cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
intracellular IEA
Inferred from Electronic Annotation
more info
 
polysomal ribosome ISO
Inferred from Sequence Orthology
more info
 
ribosome IEA
Inferred from Electronic Annotation
more info
 
synapse EXP
Inferred from Experiment
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
60S ribosomal protein L19
NP_001152955.1
NP_033104.2
XP_006532673.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159483.1NP_001152955.1  60S ribosomal protein L19 isoform 2

    See identical proteins and their annotated locations for NP_001152955.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter and 5' exon and uses a downstream start codon compared to variant 1. Isoform 2 has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AV467392, CB203522
    Consensus CDS
    CCDS48900.1
    UniProtKB/TrEMBL
    A2A547
    Related
    ENSMUSP00000103181.1, OTTMUSP00000002813, ENSMUST00000092425.10, OTTMUST00000005957
    Conserved Domains (2) summary
    cd01417
    Location:2165
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
    pfam07946
    Location:142190
    DUF1682; Protein of unknown function (DUF1682)
  2. NM_009078.2NP_033104.2  60S ribosomal protein L19 isoform 1

    See identical proteins and their annotated locations for NP_033104.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AV467392, BC089549, BU524941
    Consensus CDS
    CCDS25337.1
    UniProtKB/Swiss-Prot
    P84099
    UniProtKB/TrEMBL
    Q5I0T8
    Related
    ENSMUSP00000017548.6, OTTMUSP00000002812, ENSMUST00000017548.6, OTTMUST00000005956
    Conserved Domains (2) summary
    cd01417
    Location:4167
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
    pfam07946
    Location:144192
    DUF1682; Protein of unknown function (DUF1682)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    98023080..98030493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532610.3XP_006532673.1  60S ribosomal protein L19 isoform X1

    See identical proteins and their annotated locations for XP_006532673.1

    UniProtKB/TrEMBL
    A2A547
    Conserved Domains (2) summary
    cd01417
    Location:2165
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
    pfam07946
    Location:142190
    DUF1682; Protein of unknown function (DUF1682)
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