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Rgs16 regulator of G-protein signaling 16 [ Mus musculus (house mouse) ]

Gene ID: 19734, updated on 18-Apr-2024

Summary

Official Symbol
Rgs16provided by MGI
Official Full Name
regulator of G-protein signaling 16provided by MGI
Primary source
MGI:MGI:108407
See related
Ensembl:ENSMUSG00000026475 AllianceGenome:MGI:108407
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rgsr; Rgs14
Summary
Enables GTPase activator activity. Involved in G protein-coupled receptor signaling pathway and positive regulation of GTPase activity. Is intrinsic component of membrane. Is expressed in several structures, including central nervous system; limb mesenchyme; lip; neural retina; and skeletal musculature. Orthologous to human RGS16 (regulator of G protein signaling 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E18 (RPKM 12.8), CNS E11.5 (RPKM 10.4) and 15 other tissues See more
Orthologs
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Genomic context

Location:
1 G3; 1 65.43 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (153616099..153621212)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (153740353..153745468)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 8 Neighboring gene STARR-positive B cell enhancer mm9_chr1:155538364-155538664 Neighboring gene STARR-positive B cell enhancer mm9_chr1:155543174-155543475 Neighboring gene RIKEN cDNA C230024C17 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:155593298-155593499 Neighboring gene STARR-positive B cell enhancer ABC_E5824 Neighboring gene STARR-positive B cell enhancer ABC_E9185 Neighboring gene STARR-positive B cell enhancer mm9_chr1:155598826-155599127 Neighboring gene ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) Neighboring gene regulator of G-protein signaling like 1 Neighboring gene predicted gene, 41974

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (5)  1 citation
  • Endonuclease-mediated (4) 

Pathways from PubChem

General protein information

Preferred Names
regulator of G-protein signaling 16
Names
A28-RGS14P
RGS-R
retinal-specific RGS
retinally abundant regulator of G-protein signaling

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011267.4NP_035397.2  regulator of G-protein signaling 16

    See identical proteins and their annotated locations for NP_035397.2

    Status: VALIDATED

    Source sequence(s)
    AC154140
    Consensus CDS
    CCDS15376.1
    UniProtKB/Swiss-Prot
    O09091, P97420, P97428, Q80V16
    UniProtKB/TrEMBL
    Q542U0
    Related
    ENSMUSP00000027748.8, ENSMUST00000027748.8
    Conserved Domains (1) summary
    cd08710
    Location:65178
    RGS_RGS16; Regulator of G protein signaling (RGS) domain found in the RGS16 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    153616099..153621212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)