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FAM24B family with sequence similarity 24 member B [ Homo sapiens (human) ]

Gene ID: 196792, updated on 23-Nov-2021

Summary

Official Symbol
FAM24Bprovided by HGNC
Official Full Name
family with sequence similarity 24 member Bprovided by HGNC
Primary source
HGNC:HGNC:23475
See related
Ensembl:ENSG00000213185
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in kidney (RPKM 3.6), testis (RPKM 3.5) and 23 other tissues See more
Orthologs
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Genomic context

See FAM24B in Genome Data Viewer
Location:
10q26.13
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (122849078..122879641, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (124608594..124639157, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene deleted in malignant brain tumors 1 like 1 (pseudogene) Neighboring gene FAM24B-CUZD1 readthrough Neighboring gene CUB and zona pellucida like domains 1 Neighboring gene Sharpr-MPRA regulatory region 14360 Neighboring gene C10orf88B (pseudogene) Neighboring gene Sharpr-MPRA regulatory region 13232 Neighboring gene family with sequence similarity 24 member A Neighboring gene chromosome 10 open reading frame 88

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough FAM24B-CUZD1

Readthrough gene: FAM24B-CUZD1, Included gene: CUZD1

Homology

Clone Names

  • MGC45962, DKFZp667I0323

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204364.1NP_001191293.1  protein FAM24B precursor

    See identical proteins and their annotated locations for NP_001191293.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC073585, BC031343, BU602099, CB410280
    Consensus CDS
    CCDS31303.1
    UniProtKB/Swiss-Prot
    Q8N5W8
    Related
    ENSP00000357892.1, ENST00000368896.1
    Conserved Domains (1) summary
    pfam15193
    Location:2294
    FAM24; FAM24 family
  2. NM_152644.3NP_689857.2  protein FAM24B precursor

    See identical proteins and their annotated locations for NP_689857.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the supported protein. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC073585, AV762334, BC031343, BG490871, CB410280
    Consensus CDS
    CCDS31303.1
    UniProtKB/Swiss-Prot
    Q8N5W8
    Related
    ENSP00000357894.3, ENST00000368898.8
    Conserved Domains (1) summary
    pfam15193
    Location:2294
    FAM24; FAM24 family

RNA

  1. NR_037911.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because it lacks a significant portion of the coding region, including the start codon, as found in variant 1.
    Source sequence(s)
    AC073585, BC031343, BU958134, CB410280
    Related
    ENST00000462859.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    122849078..122879641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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