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Ranbp1 RAN binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 19385, updated on 27-Feb-2024

Summary

Official Symbol
Ranbp1provided by MGI
Official Full Name
RAN binding protein 1provided by MGI
Primary source
MGI:MGI:96269
See related
Ensembl:ENSMUSG00000005732 AllianceGenome:MGI:96269
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Htf9a
Summary
Predicted to enable GDP-dissociation inhibitor activity. Predicted to contribute to GTPase activator activity. Acts upstream of or within positive regulation of mitotic centrosome separation and spindle organization. Located in centrosome and cytoplasm. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; head mesenchyme; and sensory organ. Orthologous to human RANBP1 (RAN binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 250.8), liver E14 (RPKM 112.5) and 27 other tissues See more
Orthologs
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Genomic context

See Ranbp1 in Genome Data Viewer
Location:
16 A3; 16 11.3 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (18057843..18066558, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (18239979..18248694, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 188 Neighboring gene zinc finger, DHHC domain containing 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:18231149-18231350 Neighboring gene predicted gene, 25777 Neighboring gene STARR-positive B cell enhancer ABC_E8621 Neighboring gene TRM2 tRNA methyltransferase 2A Neighboring gene DGCR8, microprocessor complex subunit Neighboring gene microRNA 1306

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GDP-dissociation inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in axon cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane bounded cell projection cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ran-specific GTPase-activating protein
Names
Htf9-a/RanBP1
hpaII tiny fragments locus 9a protein
ran-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011239.2NP_035369.2  ran-specific GTPase-activating protein

    See identical proteins and their annotated locations for NP_035369.2

    Status: PROVISIONAL

    Source sequence(s)
    AK166642
    Consensus CDS
    CCDS37280.1
    UniProtKB/Swiss-Prot
    P34022, P34023, Q3TL81, Q9D894, Q9DCA3
    UniProtKB/TrEMBL
    Q3U6M5
    Related
    ENSMUSP00000111309.4, ENSMUST00000115645.10
    Conserved Domains (1) summary
    cd13179
    Location:24160
    RanBD_RanBP1; Ran-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    18057843..18066558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)