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Ptprcap protein tyrosine phosphatase receptor type C polypeptide-associated protein [ Mus musculus (house mouse) ]

Gene ID: 19265, updated on 21-Apr-2024

Summary

Official Symbol
Ptprcapprovided by MGI
Official Full Name
protein tyrosine phosphatase receptor type C polypeptide-associated proteinprovided by MGI
Primary source
MGI:MGI:97811
See related
Ensembl:ENSMUSG00000045826 AllianceGenome:MGI:97811
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LPAP; LSM-1; CD-45-AP
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in bone marrow; embryo; spleen; thymus; and thymus primordium. Orthologous to human PTPRCAP (protein tyrosine phosphatase receptor type C associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in thymus adult (RPKM 458.8), spleen adult (RPKM 332.6) and 2 other tissues See more
Orthologs
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Genomic context

Location:
19 A; 19 3.86 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (4204645..4206709)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (4154646..4156710)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 152 Neighboring gene STARR-positive B cell enhancer ABC_E11665 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4148564-4148673 Neighboring gene coronin, actin binding protein 1B Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4155019-4155206 Neighboring gene STARR-positive B cell enhancer ABC_E5675 Neighboring gene ribosomal protein S6 kinase, polypeptide 2 Neighboring gene carnosine synthase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (1) 

General protein information

Preferred Names
protein tyrosine phosphatase receptor type C-associated protein
Names
CD45-AP
CD45-associated protein
PTPRC-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016933.3NP_058629.2  protein tyrosine phosphatase receptor type C-associated protein

    See identical proteins and their annotated locations for NP_058629.2

    Status: VALIDATED

    Source sequence(s)
    AA265746, AI323196, AI627045, AW049152, BB840651
    Consensus CDS
    CCDS37884.1
    UniProtKB/Swiss-Prot
    Q64697
    UniProtKB/TrEMBL
    Q542J3
    Related
    ENSMUSP00000053412.9, ENSMUST00000061086.9
    Conserved Domains (1) summary
    pfam15713
    Location:58197
    PTPRCAP; Protein tyrosine phosphatase receptor type C-associated

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    4204645..4206709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)