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clec-60 VWFA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191384, updated on 18-Sep-2024

Summary

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Official Symbol
clec-60
Official Full Name
VWFA domain-containing protein
Primary source
WormBase:WBGene00014046
Locus tag
CELE_ZK666.6
See related
AllianceGenome:WB:WBGene00014046
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to Gram-positive bacterium. Is expressed in intestine. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (10480043..10481874, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Pepsin-I3 domain-containing protein Neighboring gene VWFA domain-containing protein Neighboring gene pseudo Neighboring gene DUF4033 domain-containing protein Neighboring gene Na_H_antiporter domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distinct transcriptional response of Caenorhabditis elegans to different exposure routes of perfluorooctane sulfonic acid. Stylianou M, et al. Environ Res, 2019 Jan. PMID 30388497
  2. Lactobacillus-derived extracellular vesicles enhance host immune responses against vancomycin-resistant enterococci. Li M, et al. BMC Microbiol, 2017 Mar 14. PMID 28288575, Free PMC Article
  3. Investigation into in vitro and in vivo models using intestinal epithelial IPEC-J2 cells and Caenorhabditis elegans for selecting probiotic candidates to control porcine enterotoxigenic Escherichia coli. Zhou M, et al. J Appl Microbiol, 2014 Jul. PMID 24674595
  4. Regulation of Caenorhabditis elegans and Pseudomonas aeruginosa machinery during interactions. Vigneshkumar B, et al. Arch Microbiol, 2012 Apr. PMID 21909805
  5. Caenorhabditis elegans as a model for studying Cronobacter sakazakii ATCC BAA-894 pathogenesis. Sivamaruthi BS, et al. J Basic Microbiol, 2011 Oct. PMID 21656805

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
VWFA domain-containing protein
NP_496259.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10480043..10481874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063858.4 → NP_496259.1  VWFA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496259.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23564
    Conserved Domains (2) summary
    smart00034
    Location:238 → 384
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    cl00057
    Location:24 → 216
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
Heading Accession and Version

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