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LPAR1 lysophosphatidic acid receptor 1 [ Homo sapiens (human) ]

Gene ID: 1902, updated on 23-Nov-2023

Summary

Official Symbol
LPAR1provided by HGNC
Official Full Name
lysophosphatidic acid receptor 1provided by HGNC
Primary source
HGNC:HGNC:3166
See related
Ensembl:ENSG00000198121 MIM:602282; AllianceGenome:HGNC:3166
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EDG2; LPA1; VZG1; edg-2; vzg-1; Gpcr26; Mrec1.3; rec.1.3
Summary
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]
Expression
Ubiquitous expression in brain (RPKM 14.7), placenta (RPKM 8.1) and 22 other tissues See more
Orthologs
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Genomic context

See LPAR1 in Genome Data Viewer
Location:
9q31.3
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (110873263..111038998, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (123044905..123210649, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (113635543..113801278, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr9:113490321-113490840 Neighboring gene muscle associated receptor tyrosine kinase Neighboring gene Sharpr-MPRA regulatory region 6532 Neighboring gene uncharacterized LOC107987115 Neighboring gene ribosomal protein S21 pseudogene 5 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:113544666-113545865 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:113553096-113553668 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28787 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28788 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105418 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105435 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105449 Neighboring gene RNA, U6 small nuclear 432, pseudogene Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105469 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28790 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28789 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28791 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20175 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:113715081-113715580 Neighboring gene uncharacterized LOC124902248 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20176 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28792 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:113861264-113862248 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105528 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105563 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105573 Neighboring gene RNY4 pseudogene 18 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105610 Neighboring gene VISTA enhancer hs1447 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105661 Neighboring gene microRNA 7702

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
EBI GWAS Catalog
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
EBI GWAS Catalog
Multiple loci are associated with white blood cell phenotypes.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables G-protein alpha-subunit binding IEA
Inferred from Electronic Annotation
more info
 
enables PDZ domain binding IEA
Inferred from Electronic Annotation
more info
 
enables lysophosphatidic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lysophosphatidic acid receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lysophosphatidic acid receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lysophosphatidic acid receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
involved_in activation of phospholipase C activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in bleb assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in calmodulin dependent kinase signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to 1-oleoyl-sn-glycerol 3-phosphate IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to oxygen levels IEA
Inferred from Electronic Annotation
more info
 
involved_in cerebellum development IEA
Inferred from Electronic Annotation
more info
 
involved_in corpus callosum development IEA
Inferred from Electronic Annotation
more info
 
involved_in myelination IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cilium assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in oligodendrocyte development IEA
Inferred from Electronic Annotation
more info
 
involved_in optic nerve development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of Rho protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of canonical NF-kappaB signal transduction IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in positive regulation of cytosolic calcium ion concentration TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of smooth muscle cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of stress fiber assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of cell shape ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of postsynaptic neurotransmitter receptor internalization IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of synaptic vesicle cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
located_in presynaptic membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lysophosphatidic acid receptor 1
Names
LPA receptor 1
LPA-1
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
lysophosphatidic acid receptor Edg-2
ventricular zone gene 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001351397.2NP_001338326.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DA479098
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001351398.2NP_001338327.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DA088664, DA479098
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_001351399.2NP_001338328.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DA479098
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  4. NM_001351400.2NP_001338329.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DA088664, DC327578
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  5. NM_001351401.2NP_001338330.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DC327578, DC340753, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  6. NM_001351402.2NP_001338331.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  7. NM_001351403.2NP_001338332.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DC327578
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  8. NM_001351404.2NP_001338333.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DC327578, DC340753
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  9. NM_001351405.2NP_001338334.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DC327578, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  10. NM_001351406.2NP_001338335.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DB477196, DC325182
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  11. NM_001351407.2NP_001338336.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DA088664, DB477196, DC325182
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  12. NM_001351408.2NP_001338337.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DB477196, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  13. NM_001351409.2NP_001338338.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DB477196, DC340753, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  14. NM_001351410.2NP_001338339.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, AK290287, BC036034, DB477196, DC418941, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  15. NM_001351411.2NP_001338340.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DB477196, DC325182, DC340753
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Related
    ENSP00000506912.1, ENST00000683809.1
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  16. NM_001351412.2NP_001338341.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, CN360217, DB477196, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  17. NM_001351413.2NP_001338342.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, CN360217, DB477196, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  18. NM_001351414.2NP_001338343.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DB477196, DC340753, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  19. NM_001351415.2NP_001338344.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, AK290287, BC036034, DA088664, DC325182, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  20. NM_001351416.2NP_001338345.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, AK290287, BC036034, DC418941
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  21. NM_001351417.2NP_001338346.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, BC036034, DC340753
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  22. NM_001351418.2NP_001338347.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, BC036034, CN360217, DB477196, DC340753, DC422078
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  23. NM_001351419.2NP_001338348.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, BC036034, DC340753
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  24. NM_001351420.2NP_001338349.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AI674417, AK022808, BC036034, DA327368
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  25. NM_001387470.1NP_001374399.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  26. NM_001387471.1NP_001374400.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  27. NM_001387472.1NP_001374401.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  28. NM_001387473.1NP_001374402.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  29. NM_001387474.1NP_001374403.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  30. NM_001387475.1NP_001374404.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  31. NM_001387476.1NP_001374405.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  32. NM_001387477.1NP_001374406.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  33. NM_001387478.1NP_001374407.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  34. NM_001387479.1NP_001374408.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  35. NM_001387480.1NP_001374409.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  36. NM_001387481.1NP_001374410.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  37. NM_001387482.1NP_001374411.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  38. NM_001387483.1NP_001374412.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  39. NM_001387484.1NP_001374413.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  40. NM_001387485.1NP_001374414.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  41. NM_001387486.1NP_001374415.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  42. NM_001387487.1NP_001374416.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  43. NM_001387488.1NP_001374417.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  44. NM_001387489.1NP_001374418.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  45. NM_001387490.1NP_001374419.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  46. NM_001387491.1NP_001374420.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  47. NM_001387492.1NP_001374421.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  48. NM_001387493.1NP_001374422.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  49. NM_001387494.1NP_001374423.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  50. NM_001387495.1NP_001374424.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  51. NM_001387496.1NP_001374425.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  52. NM_001387497.1NP_001374426.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  53. NM_001387498.1NP_001374427.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  54. NM_001387501.1NP_001374430.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  55. NM_001387502.1NP_001374431.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  56. NM_001387503.1NP_001374432.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  57. NM_001387504.1NP_001374433.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  58. NM_001387505.1NP_001374434.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  59. NM_001387506.1NP_001374435.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  60. NM_001387507.1NP_001374436.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  61. NM_001387508.1NP_001374437.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  62. NM_001387509.1NP_001374438.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  63. NM_001387510.1NP_001374439.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  64. NM_001387511.1NP_001374440.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  65. NM_001387512.1NP_001374441.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  66. NM_001387513.1NP_001374442.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  67. NM_001387514.1NP_001374443.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  68. NM_001387515.1NP_001374444.1  lysophosphatidic acid receptor 1 isoform a

    Status: REVIEWED

    Source sequence(s)
    AL157881, AL442064
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Related
    ENSP00000363552.1, ENST00000374430.6
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  69. NM_001387516.1NP_001374445.1  lysophosphatidic acid receptor 1 isoform b

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    UniProtKB/TrEMBL
    B4DQ18, Q6GPG7
    Conserved Domains (1) summary
    cd15344
    Location:32304
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  70. NM_001387517.1NP_001374446.1  lysophosphatidic acid receptor 1 isoform b

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL157881, AL442064
    UniProtKB/TrEMBL
    B4DQ18, Q6GPG7
    Conserved Domains (1) summary
    cd15344
    Location:32304
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  71. NM_001387518.1NP_001374447.1  lysophosphatidic acid receptor 1 isoform b

    Status: REVIEWED

    Source sequence(s)
    AL157881, AL442064
    UniProtKB/TrEMBL
    B4DQ18, Q6GPG7
    Conserved Domains (1) summary
    cd15344
    Location:32304
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  72. NM_001387519.1NP_001374448.1  lysophosphatidic acid receptor 1 isoform c

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL442064
    Conserved Domains (2) summary
    cd14964
    Location:5177
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:50267
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  73. NM_001387520.1NP_001374449.1  lysophosphatidic acid receptor 1 isoform c

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL442064
    Conserved Domains (2) summary
    cd14964
    Location:5177
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:50267
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  74. NM_001387521.1NP_001374450.1  lysophosphatidic acid receptor 1 isoform c

    Status: REVIEWED

    Source sequence(s)
    AC007157, AL442064
    Conserved Domains (2) summary
    cd14964
    Location:5177
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:50267
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  75. NM_001401.5NP_001392.2  lysophosphatidic acid receptor 1 isoform a

    See identical proteins and their annotated locations for NP_001392.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, BC036034
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Related
    ENSP00000351755.4, ENST00000358883.8
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
  76. NM_057159.4NP_476500.1  lysophosphatidic acid receptor 1 isoform a

    See identical proteins and their annotated locations for NP_476500.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
    Source sequence(s)
    AC007157, AI674417, AK022808, BC030615, BC036034
    Consensus CDS
    CCDS6777.1
    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0
    Related
    ENSP00000363553.3, ENST00000374431.7
    Conserved Domains (1) summary
    cd15344
    Location:50322
    7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    110873263..111038998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422903.1XP_047278859.1  lysophosphatidic acid receptor 1 isoform X1

    UniProtKB/Swiss-Prot
    B4DK36, O00656, O00722, P78351, Q92633
    UniProtKB/TrEMBL
    B4DQ18, Q5VZX0

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    123044905..123210649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)