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sysm-1 ShKT domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188838, updated on 23-May-2024

Summary

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Gene symbol
sysm-1
Gene description
ShKT domain-containing protein
Primary source
WormBase:WBGene00011979
Locus tag
CELE_T24B8.5
See related
AllianceGenome:WB:WBGene00011979
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in innate immune response. Is expressed in intestine. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See sysm-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (9082626..9083193, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Helix-loop-helix protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Reddy KC, et al. Science, 2009 Jan 16. PMID 19150845, Free PMC Article
  2. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Troemel ER, et al. PLoS Genet, 2006 Nov 10. PMID 17096597, Free PMC Article
  3. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Styer KL, et al. Science, 2008 Oct 17. PMID 18801967, Free PMC Article
  4. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in antibacterial innate immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in innate immune response HEP PubMed 

General protein information

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Preferred Names
ShKT domain-containing protein
NP_495937.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9082626..9083193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063536.5 → NP_495937.2  ShKT domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495937.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22714
Nucleotide Protein
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