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C46A5.1 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183497, updated on 18-Sep-2024

Summary

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Official Symbol
C46A5.1
Official Full Name
Tyrosine-protein phosphatase domain-containing protein
Primary source
WormBase:WBGene00016698
Locus tag
CELE_C46A5.1
See related
AllianceGenome:WB:WBGene00016698
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Orthologous to human PTPRG (protein tyrosine phosphatase receptor type G) and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (7763931..7767112)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Double-Strand Break factor Neighboring gene Uncharacterized protein Neighboring gene Acid-sensing ion channel 1-like Neighboring gene ncRNA Neighboring gene Rentinal Degeneration 3-Like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tyrosine-protein phosphatase domain-containing protein
NP_501277.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7763931..7767112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068876.5 → NP_501277.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501277.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18652
    Conserved Domains (2) summary
    cd00047
    Location:245 → 468
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:243 → 468
    Y_phosphatase; Protein-tyrosine phosphatase
Nucleotide Protein
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