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npr-11 Putative neuropeptide Y receptor 11 [ Caenorhabditis elegans ]

Gene ID: 182921, updated on 18-Sep-2024

Summary

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Official Symbol
npr-11
Official Full Name
Putative neuropeptide Y receptor 11
Primary source
WormBase:WBGene00016110
Locus tag
CELE_C25G6.5
See related
AllianceGenome:WB:WBGene00016110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in neurons. Orthologous to human NPY6R (neuropeptide Y receptor Y6 (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
8
Sequence:
Chromosome: X; NC_003284.9 (1251815..1255647, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene AMP-dependent synthetase/ligase domain-containing protein Neighboring gene Tetraspanin Neighboring gene DUF19 domain-containing protein Neighboring gene Protein sleepless Neighboring gene NF-kappa-B inhibitor-interacting Ras-like protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. NPY/NPF-Related Neuropeptide FLP-34 Signals from Serotonergic Neurons to Modulate Aversive Olfactory Learning in Caenorhabditis elegans. Fadda M, et al. J Neurosci, 2020 Jul 29. PMID 32576621, Free PMC Article
  2. Structural Perspective on Ancient Neuropeptide Y-like System reveals Hallmark Features for Peptide Recognition and Receptor Activation. Gershkovich MM, et al. J Mol Biol, 2021 Jun 25. PMID 33865871, Free PMC Article
  3. Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons. Chalasani SH, et al. Nat Neurosci, 2010 May. PMID 20364145, Free PMC Article
  4. Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi. Keating CD, et al. Curr Biol, 2003 Sep 30. PMID 14521838
  5. The long and the short of it - a perspective on peptidergic regulation of circuits and behaviour. Jékely G, et al. J Exp Biol, 2018 Feb 8. PMID 29439060

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural Perspective on Ancient Neuropeptide Y-like System reveals Hallmark Features for Peptide Recognition and Receptor Activation.
    Title: Structural Perspective on Ancient Neuropeptide Y-like System reveals Hallmark Features for Peptide Recognition and Receptor Activation.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables neuropeptide Y receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative neuropeptide Y receptor 11
NP_508234.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    1251815..1255647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075833.5 → NP_508234.2  Putative neuropeptide Y receptor 11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508234.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18179
    Conserved Domains (2) summary
    pfam00001
    Location:56 → 325
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:48 → 192
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18179.2

Gene LinkOut

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