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rfc-1 Replication factor C subunit 1 [ Caenorhabditis elegans ]

Gene ID: 179967, updated on 23-Nov-2023

Summary

Gene symbol
rfc-1
Gene description
Replication factor C subunit 1
Primary source
WormBase:WBGene00004337
Locus tag
CELE_C54G10.2
See related
AllianceGenome:WB:WBGene00004337
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Predicted to be involved in DNA repair and DNA replication. Predicted to be part of DNA replication factor C complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in West Nile fever. Orthologous to human RFC1 (replication factor C subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See rfc-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (14642667..14645979, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CX domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ATP-binding cassette sub-family D member 4 Neighboring gene Mitochondrial carnitine/acylcarnitine carrier protein CACL Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA clamp loader activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of DNA replication factor C complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Replication factor C subunit 1
NP_001256606.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14642667..14645979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269677.2NP_001256606.1  Replication factor C subunit 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256606.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18841
    Conserved Domains (3) summary
    PRK04195
    Location:277805
    PRK04195; replication factor C large subunit; Provisional
    pfam00004
    Location:344453
    AAA; ATPase family associated with various cellular activities (AAA)
    pfam08519
    Location:597750
    RFC1; Replication factor RFC1 C terminal domain

RNA

  1. NR_069988.1 RNA Sequence

    Status: REVIEWED