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decr-1.1 putative oxidoreductase F53C11.3 [ Caenorhabditis elegans ]

Gene ID: 179872, updated on 12-Jun-2024

Summary

Gene symbol
decr-1.1
Gene description
putative oxidoreductase F53C11.3
Locus tag
CELE_F53C11.3
See related
AllianceGenome:WB:WBGene00009973
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be active in mitochondrion. Is expressed in intestine. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See decr-1.1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (13782399..13784109)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene TIL domain-containing protein Neighboring gene pseudo Neighboring gene SH2 domain-containing protein Neighboring gene USP domain-containing protein;Zf-C3H1 domain-containing protein Neighboring gene Fibronectin type-III domain-containing protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 2,4-dienoyl-CoA reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
putative oxidoreductase F53C11.3
NP_506413.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13782399..13784109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074012.7NP_506413.1  putative oxidoreductase F53C11.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506413.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93761
    Conserved Domains (2) summary
    PRK07677
    Location:40273
    PRK07677; short chain dehydrogenase; Provisional
    cd05369
    Location:40275
    TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR