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lbp-9 Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9 [ Caenorhabditis elegans ]

Gene ID: 178686, updated on 18-Sep-2024

Summary

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Official Symbol
lbp-9
Official Full Name
Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9
Primary source
WormBase:WBGene00021486
Locus tag
CELE_Y40B10A.1
See related
AllianceGenome:WB:WBGene00021486
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1G. Orthologous to several human genes including FABP4 (fatty acid binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (2068449..2069142)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene O-methyltransferase Neighboring gene Catechol O-methyltransferase domain-containing protein 1 Neighboring gene Nuclear hormone receptor family member nhr-86 Neighboring gene Lipase_GDSL domain-containing protein;Phospholipase B1, membrane-associated Neighboring gene Glycosyltransferase family 92 protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene C2H2-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis. Ha MK, et al. Proteomics, 2006 Jun. PMID 16673436
  2. ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. O'Rourke EJ, et al. Genes Dev, 2013 Feb 15. PMID 23392608, Free PMC Article
  3. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684
  4. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Van Gilst MR, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157872, Free PMC Article
  5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables fatty acid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9
NP_001033511.1
  • Confirmed by transcript evidence
NP_001033512.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2068449..2069142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038422.7 → NP_001033511.1  Fatty acid-binding protein homolog 9 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001033511.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q965W1
    Conserved Domains (1) summary
    pfam00061
    Location:23 → 151
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

  2. NM_001038423.6 → NP_001033512.1  Cytosolic fatty-acid binding proteins domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001033512.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3LFN1
    Conserved Domains (1) summary
    cd00742
    Location:6 → 135
    FABP; intracellular fatty acid-binding protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q965W1.1

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