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Morc1 microrchidia 1 [ Mus musculus (house mouse) ]

Gene ID: 17450, updated on 8-Feb-2024

Summary

Official Symbol
Morc1provided by MGI
Official Full Name
microrchidia 1provided by MGI
Primary source
MGI:MGI:1316740
See related
Ensembl:ENSMUSG00000022652 AllianceGenome:MGI:1316740
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Morc
Summary
Predicted to enable zinc ion binding activity. Involved in negative regulation of gene expression. Acts upstream of or within several processes, including behavioral fear response; gamete generation; and regulation of nucleobase-containing compound metabolic process. Located in nucleus. Is active in male germ cell nucleus. Is expressed in esophagus; head mesenchyme; musculoskeletal system; and sensory organ. Used to study endogenous depression. Orthologous to human MORC1 (MORC family CW-type zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Morc1 in Genome Data Viewer
Location:
16 B5; 16 30.75 cM
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (48251600..48451268)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (48431237..48630905)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 2 Neighboring gene STARR-seq mESC enhancer starr_40947 Neighboring gene predicted gene 5485 Neighboring gene STARR-seq mESC enhancer starr_40948 Neighboring gene STARR-seq mESC enhancer starr_40950 Neighboring gene STARR-seq mESC enhancer starr_40952 Neighboring gene STARR-seq mESC enhancer starr_40956 Neighboring gene STARR-seq mESC enhancer starr_40960 Neighboring gene predicted gene, 41458 Neighboring gene T cell receptor associated transmembrane adaptor 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:48788868-48789191 Neighboring gene TWIST neighbor pseudogene Neighboring gene resistin like beta

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Transgenic (1)  1 citation
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
MORC family CW-type zinc finger protein 1
Names
protein microrchidia

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010816.1NP_034946.1  MORC family CW-type zinc finger protein 1

    See identical proteins and their annotated locations for NP_034946.1

    Status: PROVISIONAL

    Source sequence(s)
    AF084945
    Consensus CDS
    CCDS37351.1
    UniProtKB/Swiss-Prot
    Q9WVL5
    Related
    ENSMUSP00000023330.7, ENSMUST00000023330.8
    Conserved Domains (2) summary
    pfam07496
    Location:481528
    zf-CW; CW-type Zinc Finger
    cl00075
    Location:27159
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    48251600..48451268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)