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cah-2 Putative carbonic anhydrase-like protein 2 [ Caenorhabditis elegans ]

Gene ID: 174218, updated on 18-Sep-2024

Summary

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Official Symbol
cah-2
Official Full Name
Putative carbonic anhydrase-like protein 2
Primary source
WormBase:WBGene00000280
Locus tag
CELE_D1022.8
See related
AllianceGenome:WB:WBGene00000280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in extracellular region. Is expressed in intestine; muscle cell; neurons; pharynx; and vulva. Orthologous to human CA10 (carbonic anhydrase 10). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (7480751..7483109, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene FYVE-type domain-containing protein Neighboring gene E2 ubiquitin-conjugating enzyme Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a nuclear carbonic anhydrase in Caenorhabditis elegans. Sherman TA, et al. Biochim Biophys Acta, 2012 Apr. PMID 22245567, Free PMC Article
  2. Molecular and biochemical analysis of the α class carbonic anhydrases in Caenorhabditis elegans. Fasseas MK, et al. Mol Biol Rep, 2011 Mar. PMID 20842438
  3. Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. Mathew ND, et al. J Toxicol, 2011. PMID 22131987, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydro-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative carbonic anhydrase-like protein 2
NP_495567.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7480751..7483109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063166.7 → NP_495567.3  Putative carbonic anhydrase-like protein 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495567.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18932
    Conserved Domains (1) summary
    cd03121
    Location:16 → 275
    alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18932.3

Gene LinkOut

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