U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pri-2 DNA primase large subunit [ Caenorhabditis elegans ]

Gene ID: 173122, updated on 23-Nov-2023

Summary

Gene symbol
pri-2
Gene description
DNA primase large subunit
Primary source
WormBase:WBGene00004181
Locus tag
CELE_W02D9.1
See related
AllianceGenome:WB:WBGene00004181
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable 4 iron, 4 sulfur cluster binding activity; DNA binding activity; and metal ion binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be part of alpha DNA polymerase:primase complex. Orthologous to human PRIM2 (DNA primase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See pri-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (12528304..12532135, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Mitochondrial transcription termination factor family protein Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene Protein YIPF Neighboring gene HMG box domain-containing protein

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA replication, synthesis of RNA primer IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA replication, synthesis of RNA primer IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of nematode male tail tip morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of alpha DNA polymerase:primase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA primase large subunit
NP_001251922.1
  • Confirmed by transcript evidence
NP_001251923.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    12528304..12532135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001264993.2NP_001251922.1  DNA primase large subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251922.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02334
    Conserved Domains (1) summary
    cd07322
    Location:43475
    PriL_PriS_Eukaryotic; Eukaryotic core primase: Large subunit, PriL
  2. NM_001264994.3NP_001251923.1  DNA primase large subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251923.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D7SFP4
    Conserved Domains (1) summary
    cd07322
    Location:3294
    PriL_PriS_Eukaryotic; Eukaryotic core primase: Large subunit, PriL