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Foxd2 forkhead box D2 [ Mus musculus (house mouse) ]

Gene ID: 17301, updated on 18-Apr-2024

Summary

Official Symbol
Foxd2provided by MGI
Official Full Name
forkhead box D2provided by MGI
Primary source
MGI:MGI:1347471
See related
Ensembl:ENSMUSG00000055210 AllianceGenome:MGI:1347471
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mf2
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; integumental system; and sensory organ. Orthologous to human FOXD2 (forkhead box D2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
4 D1; 4 52.73 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (114763477..114766095, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (114906280..114908898, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9130410C08 gene Neighboring gene predicted gene 12830 Neighboring gene predicted gene, 23230 Neighboring gene forkhead box D2, opposite strand Neighboring gene forkhead box E3

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 
  • Targeted (1)  1 citation

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
forkhead box protein D2
Names
MF-2
mesoderm/mesenchyme forkhead 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008593.3NP_032619.1  forkhead box protein D2

    See identical proteins and their annotated locations for NP_032619.1

    Status: VALIDATED

    Source sequence(s)
    AL670035
    Consensus CDS
    CCDS18482.1
    UniProtKB/Swiss-Prot
    A2AD43, O35392
    Related
    ENSMUSP00000066868.4, ENSMUST00000068654.5
    Conserved Domains (1) summary
    pfam00250
    Location:129215
    Forkhead; Forkhead domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    114763477..114766095 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)