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Ccndbp1 cyclin D-type binding-protein 1 [ Mus musculus (house mouse) ]

Gene ID: 17151, updated on 9-May-2024

Summary

Official Symbol
Ccndbp1provided by MGI
Official Full Name
cyclin D-type binding-protein 1provided by MGI
Primary source
MGI:MGI:109595
See related
Ensembl:ENSMUSG00000023572 AllianceGenome:MGI:109595
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DIP1; GCIP; Maid; SECC-8; SSEC-8
Summary
Predicted to be involved in regulation of cell cycle. Predicted to be located in nuclear body. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CCNDBP1 (cyclin D1 binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 18.2), bladder adult (RPKM 11.1) and 28 other tissues See more
Orthologs
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Genomic context

See Ccndbp1 in Genome Data Viewer
Location:
2 E5; 2 60.37 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120838925..120847374)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (121008395..121016912)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene expressed sequence AV039307 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1 Neighboring gene STARR-positive B cell enhancer ABC_E5971 Neighboring gene STARR-positive B cell enhancer ABC_E147 Neighboring gene transmembrane protein 62 Neighboring gene small nucleolar RNA, C/D box 3B, pseudogene 2 Neighboring gene erythrocyte membrane protein band 4.2 Neighboring gene WW domain binding protein 2 pseudogene Neighboring gene transglutaminase 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
cyclin-D1-binding protein 1
Names
grap2 and cyclin-D-interacting protein
maternal Id-like protein
maternal inhibition of differentiation
stage specific embryonic cDNA-8 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355127.2NP_001342056.1  cyclin-D1-binding protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 3' end compared to variant 1, that causes a frameshift. The resulting isoform (2) has a longer and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AL844548
    UniProtKB/TrEMBL
    A0AA74IZC9
    Related
    ENSMUSP00000125961.4, ENSMUST00000171260.4
    Conserved Domains (1) summary
    pfam13324
    Location:52305
    GCIP; Grap2 and cyclin-D-interacting
  2. NM_010761.3NP_034891.2  cyclin-D1-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_034891.2

    Status: VALIDATED

    Source sequence(s)
    AL844548
    Consensus CDS
    CCDS38213.1
    UniProtKB/Swiss-Prot
    Q3TVC7, Q3UMI3, Q61162, Q99JA7, Q99KG4
    UniProtKB/TrEMBL
    A0AA74IZC9
    Related
    ENSMUSP00000062496.9, ENSMUST00000060455.15
    Conserved Domains (1) summary
    pfam13324
    Location:52316
    GCIP; Grap2 and cyclin-D-interacting

RNA

  1. NR_185170.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL844548

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    120838925..120847374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239329.3XP_011237631.1  cyclin-D1-binding protein 1 isoform X1

    Conserved Domains (1) summary
    pfam13324
    Location:1133
    GCIP; Grap2 and cyclin-D-interacting