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Ubn1 ubinuclein 1 [ Mus musculus (house mouse) ]

Gene ID: 170644, updated on 12-May-2024

Summary

Official Symbol
Ubn1provided by MGI
Official Full Name
ubinuclein 1provided by MGI
Primary source
MGI:MGI:1891307
See related
Ensembl:ENSMUSG00000039473 AllianceGenome:MGI:1891307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110029L11Rik; 2610108L02Rik
Summary
Predicted to enable DNA binding activity. Predicted to be involved in DNA replication-independent chromatin assembly. Predicted to act upstream of or within keratinocyte differentiation. Located in bicellular tight junction. Is expressed in eye; limb; and limb mesenchyme. Orthologous to human UBN1 (ubinuclein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 18.7), limb E14.5 (RPKM 10.5) and 28 other tissues See more
Orthologs
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Genomic context

See Ubn1 in Genome Data Viewer
Location:
16 A1; 16 2.49 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (4867921..4904153)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (5050057..5086289)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7426 Neighboring gene rogdi homolog Neighboring gene glyoxylate reductase 1 homolog (Arabidopsis) Neighboring gene STARR-positive B cell enhancer ABC_E1180 Neighboring gene predicted gene, 23483 Neighboring gene transmembrane protein 126A pseudogene Neighboring gene periplakin Neighboring gene SEC14-like lipid binding 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC102206

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription factor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within keratinocyte differentiation TAS
Traceable Author Statement
more info
PubMed 
involved_in nucleosome assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in bicellular tight junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
ubinuclein-1
Names
ubiquitously expressed nuclear protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356320.2NP_001343249.1  ubinuclein-1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC163723
    Consensus CDS
    CCDS88873.1
    Related
    ENSMUSP00000155263.2, ENSMUST00000229126.2
    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354573
    UBN_AB; Ubinuclein conserved middle domain
  2. NM_026666.4NP_080942.1  ubinuclein-1 isoform 1

    See identical proteins and their annotated locations for NP_080942.1

    Status: VALIDATED

    Source sequence(s)
    AK019173, AK147571, CJ246723
    Consensus CDS
    CCDS27931.1
    UniProtKB/Swiss-Prot
    Q3UUZ4, Q4G0F8, Q6P9K7, Q8BNC3, Q9CRM4, Q9CS40
    Related
    ENSMUSP00000061843.6, ENSMUST00000052449.6
    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354573
    UBN_AB; Ubinuclein conserved middle domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    4867921..4904153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521817.4XP_006521880.1  ubinuclein-1 isoform X3

    See identical proteins and their annotated locations for XP_006521880.1

    UniProtKB/Swiss-Prot
    Q3UUZ4, Q4G0F8, Q6P9K7, Q8BNC3, Q9CRM4, Q9CS40
    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354573
    UBN_AB; Ubinuclein conserved middle domain
  2. XM_006521816.4XP_006521879.1  ubinuclein-1 isoform X3

    See identical proteins and their annotated locations for XP_006521879.1

    UniProtKB/Swiss-Prot
    Q3UUZ4, Q4G0F8, Q6P9K7, Q8BNC3, Q9CRM4, Q9CS40
    Related
    ENSMUSP00000155223.2, ENSMUST00000230703.2
    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354573
    UBN_AB; Ubinuclein conserved middle domain
  3. XM_036159802.1XP_036015695.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  4. XM_036159798.1XP_036015691.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  5. XM_036159797.1XP_036015690.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  6. XM_036159804.1XP_036015697.1  ubinuclein-1 isoform X2

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  7. XM_036159800.1XP_036015693.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  8. XM_036159799.1XP_036015692.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  9. XM_036159801.1XP_036015694.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  10. XM_036159803.1XP_036015696.1  ubinuclein-1 isoform X1

    Conserved Domains (2) summary
    pfam08729
    Location:117168
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:354606
    UBN_AB; Ubinuclein conserved middle domain
  11. XM_036159805.1XP_036015698.1  ubinuclein-1 isoform X4

    Conserved Domains (1) summary
    pfam14075
    Location:1118
    UBN_AB; Ubinuclein conserved middle domain