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STKLD1 serine/threonine kinase like domain containing 1 [ Homo sapiens (human) ]

Gene ID: 169436, updated on 23-Nov-2021

Summary

Official Symbol
STKLD1provided by HGNC
Official Full Name
serine/threonine kinase like domain containing 1provided by HGNC
Primary source
HGNC:HGNC:28669
See related
Ensembl:ENSG00000198870 MIM:618530
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Sk521; SgK071; C9orf96
Expression
Biased expression in testis (RPKM 4.5), brain (RPKM 0.4) and 2 other tissues See more
Orthologs
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Genomic context

See STKLD1 in Genome Data Viewer
Location:
9q34.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (133376366..133406096)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (136243237..136271220)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene SURF1 cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene surfeit 4 Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 13 Neighboring gene Sharpr-MPRA regulatory region 9315 Neighboring gene calcium channel flower domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: SURF2

Homology

Clone Names

  • MGC43306

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine kinase-like domain-containing protein STKLD1
Names
probable inactive protein kinase-like protein SgK071
serine/threonine kinase-like domain-containing protein 1
sugen kinase 071

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153710.5NP_714921.4  serine/threonine kinase-like domain-containing protein STKLD1

    See identical proteins and their annotated locations for NP_714921.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the protein.
    Source sequence(s)
    AK131545, AL593848, BC036504
    Consensus CDS
    CCDS35169.1
    UniProtKB/Swiss-Prot
    Q8NE28
    Related
    ENSP00000361025.3, ENST00000371957.4
    Conserved Domains (1) summary
    cd00180
    Location:34292
    PKc; Catalytic domain of Protein Kinases

RNA

  1. NR_103997.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains multiple differences in the internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK131545, AL593848, BC036504

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    133376366..133406096
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646201.1 Reference GRCh38.p13 PATCHES

    Range
    202460..232190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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