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Rps2 ribosomal protein S2 [ Mus musculus (house mouse) ]

Gene ID: 16898, updated on 8-Jan-2023

Summary

Official Symbol
Rps2provided by MGI
Official Full Name
ribosomal protein S2provided by MGI
Primary source
MGI:MGI:105110
See related
Ensembl:ENSMUSG00000044533 AllianceGenome:MGI:105110
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S4; Llrep3
Summary
Predicted to enable enzyme binding activity; fibroblast growth factor binding activity; and mRNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within cellular response to interleukin-4. Is active in synapse. Is expressed in embryo; liver; and retina outer nuclear layer. Orthologous to human RPS2 (ribosomal protein S2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14.5 (RPKM 886.9), liver E14 (RPKM 881.0) and 28 other tissues See more
Orthologs
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Genomic context

See Rps2 in Genome Data Viewer
Location:
17; 17 A3.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24939037..24940901)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24718121..24721927)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 151 Neighboring gene small nucleolar RNA, H/ACA box 7 Neighboring gene small nucleolar RNA host gene 9 Neighboring gene small nucleolar RNA, H/ACA box 64 Neighboring gene NADH:ubiquinone oxidoreductase subunit B10 Neighboring gene ribosomal protein L3-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC118037, MGC118038

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables fibroblast growth factor binding ISO
Inferred from Sequence Orthology
more info
 
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to interleukin-4 IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in positive regulation of ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
40S ribosomal protein S2
Names
40S ribosomal protein S4
protein LLRep3
repeat family 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008503.5NP_032529.2  40S ribosomal protein S2

    See identical proteins and their annotated locations for NP_032529.2

    Status: VALIDATED

    Source sequence(s)
    AC154566, AK166664, BY443672
    Consensus CDS
    CCDS37493.1
    UniProtKB/Swiss-Prot
    P25444
    UniProtKB/TrEMBL
    A0A6P5Q5M5, Q58EU3
    Related
    ENSMUSP00000131474.2, ENSMUST00000170715.8
    Conserved Domains (1) summary
    PTZ00070
    Location:54273
    PTZ00070; 40S ribosomal protein S2; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24939037..24940901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)