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TENT2 terminal nucleotidyltransferase 2 [ Homo sapiens (human) ]

Gene ID: 167153, updated on 26-Oct-2022

Summary

Official Symbol
TENT2provided by HGNC
Official Full Name
terminal nucleotidyltransferase 2provided by HGNC
Primary source
HGNC:HGNC:26776
See related
Ensembl:ENSG00000164329 MIM:614121; AllianceGenome:HGNC:26776
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
APD4; GLD2; TUT2; PAPD4
Summary
Enables 5'-3' RNA polymerase activity and polynucleotide adenylyltransferase activity. Involved in RNA metabolic process and negative regulation of RNA catabolic process. Predicted to be located in nucleus. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bone marrow (RPKM 14.6), lymph node (RPKM 12.6) and 25 other tissues See more
Orthologs
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Genomic context

See TENT2 in Genome Data Viewer
Location:
5q14.1
Exon count:
22
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (79612441..79688246)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (80096704..80172520)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (78908264..78984069)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901013 Neighboring gene uncharacterized LOC105379047 Neighboring gene uncharacterized LOC124901014 Neighboring gene cardiomyopathy associated 5 Neighboring gene uncharacterized LOC102724557

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
EBI GWAS Catalog
Novel locus FER is associated with serum HMW adiponectin levels.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38499

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 5'-3' RNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables adenylyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables polynucleotide adenylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables polynucleotide adenylyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in RNA polyadenylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in RNA polyadenylation at postsynapse IEA
Inferred from Electronic Annotation
more info
 
involved_in RNA stabilization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in dark adaptation IEA
Inferred from Electronic Annotation
more info
 
involved_in hematopoietic progenitor cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in hippocampus development IEA
Inferred from Electronic Annotation
more info
 
involved_in histone mRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mRNA polyadenylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of miRNA catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in postsynaptic modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of translation at postsynapse IEA
Inferred from Electronic Annotation
more info
 
involved_in retina development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
part_of nuclear RNA-directed RNA polymerase complex IC
Inferred by Curator
more info
PubMed 
located_in perforant pathway to dendrate granule cell synapse IEA
Inferred from Electronic Annotation
more info
 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
poly(A) RNA polymerase GLD2
Names
PAP associated domain containing 4
PAP-associated domain-containing protein 4
TUTase 2
poly(A) RNA polymerase D4, non-canonical
terminal uridylyltransferase 2
NP_001107865.1
NP_001107866.1
NP_001284673.1
NP_001284674.1
NP_001336477.1
NP_001336478.1
NP_001336479.1
NP_001336480.1
NP_001336481.1
NP_001336482.1
NP_001336483.1
NP_001375022.1
NP_001375023.1
NP_001375024.1
NP_001375025.1
NP_001375026.1
NP_001375027.1
NP_001375028.1
NP_001375029.1
NP_001375030.1
NP_001375031.1
NP_001375032.1
NP_001375034.1
NP_001375035.1
NP_001375036.1
NP_001375037.1
NP_001375038.1
NP_001375039.1
NP_001375040.1
NP_001375041.1
NP_001375042.1
NP_001375043.1
NP_001375044.1
NP_001375045.1
NP_001375046.1
NP_001375047.1
NP_001375048.1
NP_001375049.1
NP_001375050.1
NP_001375051.1
NP_001375052.1
NP_001375053.1
NP_001375054.1
NP_001375055.1
NP_001375056.1
NP_001375057.1
NP_001375058.1
NP_001375059.1
NP_001375060.1
NP_001375061.1
NP_001375062.1
NP_001375063.1
NP_001375064.1
NP_001375065.1
NP_001375066.1
NP_776158.2
XP_011541522.1
XP_011541523.1
XP_011541526.1
XP_011541527.1
XP_011541531.1
XP_016864641.1
XP_047272800.1
XP_047272801.1
XP_047272802.1
XP_047272803.1
XP_047272804.1
XP_047272805.1
XP_047272806.1
XP_047272807.1
XP_047272808.1
XP_047272809.1
XP_047272810.1
XP_047272811.1
XP_047272812.1
XP_047272813.1
XP_047272814.1
XP_047272815.1
XP_047272816.1
XP_047272817.1
XP_047272818.1
XP_047272819.1
XP_047272820.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114393.3NP_001107865.1  poly(A) RNA polymerase GLD2 isoform 1

    See identical proteins and their annotated locations for NP_001107865.1

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AW302247, BC047581, DA803910, DB302918
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q6PIY7, Q8N927
    Related
    ENSP00000396861.2, ENST00000428308.6
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  2. NM_001114394.3NP_001107866.1  poly(A) RNA polymerase GLD2 isoform 1

    See identical proteins and their annotated locations for NP_001107866.1

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, DA803910, DB302918
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q6PIY7, Q8N927
    Related
    ENSP00000397563.1, ENST00000453514.6
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  3. NM_001297744.3NP_001284673.1  poly(A) RNA polymerase GLD2 isoform 2

    See identical proteins and their annotated locations for NP_001284673.1

    Status: VALIDATED

    Source sequence(s)
    AC008482, AW302247, BC047581, DB302918
    Consensus CDS
    CCDS75266.1
    UniProtKB/Swiss-Prot
    Q6PIY7
    Related
    ENSP00000393412.2, ENST00000423041.6
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  4. NM_001297745.3NP_001284674.1  poly(A) RNA polymerase GLD2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC008482, AL833136, AW302247, BC047581, DB302918
    Consensus CDS
    CCDS75265.1
    UniProtKB/TrEMBL
    D6RAF2
    Related
    ENSP00000421966.1, ENST00000504233.5
    Conserved Domains (2) summary
    cd05402
    Location:176298
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    COG5260
    Location:154425
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  5. NM_001349548.2NP_001336477.1  poly(A) RNA polymerase GLD2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AW302247, BC047581, CN348312, DA803910, DB302918
    Conserved Domains (1) summary
    cl27230
    Location:4245
    PAP_assoc; Cid1 family poly A polymerase
  6. NM_001349549.2NP_001336478.1  poly(A) RNA polymerase GLD2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, DA803910, DB302918
    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  7. NM_001349550.2NP_001336479.1  poly(A) RNA polymerase GLD2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AW302247, BC047581, CF137152, CN348312, DA803910, DB302918
    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  8. NM_001349551.2NP_001336480.1  poly(A) RNA polymerase GLD2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, DA803910, DB302918
    Conserved Domains (1) summary
    COG5260
    Location:154489
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  9. NM_001349552.2NP_001336481.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, CF137152, CN348312, DA803910, DB302918
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  10. NM_001349553.2NP_001336482.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, CF137152, CN348312, DA803910, DB302918
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  11. NM_001349554.2NP_001336483.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AL833136, AW302247, BC047581, CF137152, CN348312, DA803910, DB302918
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  12. NM_001388093.1NP_001375022.1  poly(A) RNA polymerase GLD2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  13. NM_001388094.1NP_001375023.1  poly(A) RNA polymerase GLD2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  14. NM_001388095.1NP_001375024.1  poly(A) RNA polymerase GLD2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154489
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  15. NM_001388096.1NP_001375025.1  poly(A) RNA polymerase GLD2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154489
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  16. NM_001388097.1NP_001375026.1  poly(A) RNA polymerase GLD2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154489
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  17. NM_001388098.1NP_001375027.1  poly(A) RNA polymerase GLD2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:153488
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  18. NM_001388099.1NP_001375028.1  poly(A) RNA polymerase GLD2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154478
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  19. NM_001388100.1NP_001375029.1  poly(A) RNA polymerase GLD2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154478
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  20. NM_001388101.1NP_001375030.1  poly(A) RNA polymerase GLD2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:154474
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  21. NM_001388102.1NP_001375031.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  22. NM_001388103.1NP_001375032.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  23. NM_001388105.1NP_001375034.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  24. NM_001388106.1NP_001375035.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  25. NM_001388107.1NP_001375036.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  26. NM_001388108.1NP_001375037.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  27. NM_001388109.1NP_001375038.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  28. NM_001388110.1NP_001375039.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  29. NM_001388111.1NP_001375040.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  30. NM_001388112.1NP_001375041.1  poly(A) RNA polymerase GLD2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q8N927
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  31. NM_001388113.1NP_001375042.1  poly(A) RNA polymerase GLD2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:153467
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  32. NM_001388114.1NP_001375043.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  33. NM_001388115.1NP_001375044.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  34. NM_001388116.1NP_001375045.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  35. NM_001388117.1NP_001375046.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  36. NM_001388118.1NP_001375047.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  37. NM_001388119.1NP_001375048.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  38. NM_001388120.1NP_001375049.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  39. NM_001388121.1NP_001375050.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  40. NM_001388122.1NP_001375051.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  41. NM_001388123.1NP_001375052.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  42. NM_001388124.1NP_001375053.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  43. NM_001388125.1NP_001375054.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  44. NM_001388126.1NP_001375055.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  45. NM_001388127.1NP_001375056.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  46. NM_001388128.1NP_001375057.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  47. NM_001388129.1NP_001375058.1  poly(A) RNA polymerase GLD2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75266.1
    Conserved Domains (1) summary
    COG5260
    Location:154464
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  48. NM_001388130.1NP_001375059.1  poly(A) RNA polymerase GLD2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:153463
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  49. NM_001388131.1NP_001375060.1  poly(A) RNA polymerase GLD2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:124438
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  50. NM_001388132.1NP_001375061.1  poly(A) RNA polymerase GLD2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:124434
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  51. NM_001388133.1NP_001375062.1  poly(A) RNA polymerase GLD2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Consensus CDS
    CCDS75265.1
    UniProtKB/TrEMBL
    D6RAF2
    Conserved Domains (2) summary
    cd05402
    Location:176298
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    COG5260
    Location:154425
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  52. NM_001388134.1NP_001375063.1  poly(A) RNA polymerase GLD2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (2) summary
    cd05402
    Location:176294
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    COG5260
    Location:154421
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  53. NM_001388135.1NP_001375064.1  poly(A) RNA polymerase GLD2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (2) summary
    cd05402
    Location:176294
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    COG5260
    Location:154421
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  54. NM_001388136.1NP_001375065.1  poly(A) RNA polymerase GLD2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (1) summary
    COG5260
    Location:38348
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  55. NM_001388137.1NP_001375066.1  poly(A) RNA polymerase GLD2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC008482
    Conserved Domains (2) summary
    COG5260
    Location:81270
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
    cl11966
    Location:36100
    NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
  56. NM_173797.5NP_776158.2  poly(A) RNA polymerase GLD2 isoform 1

    See identical proteins and their annotated locations for NP_776158.2

    Status: VALIDATED

    Source sequence(s)
    AC008482, AK095818, AW302247, BC047581, CN348312, DA803910, DB302918
    Consensus CDS
    CCDS4048.1
    UniProtKB/Swiss-Prot
    Q6PIY7, Q8N927
    Related
    ENSP00000296783.3, ENST00000296783.7
    Conserved Domains (1) summary
    COG5260
    Location:154468
    TRF4; DNA polymerase sigma [Replication, recombination and repair]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    79612441..79688246
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543221.4XP_011541523.1  poly(A) RNA polymerase GLD2 isoform X1

    See identical proteins and their annotated locations for XP_011541523.1

    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  2. XM_047416850.1XP_047272806.1  poly(A) RNA polymerase GLD2 isoform X3

    UniProtKB/Swiss-Prot
    Q8N927
  3. XM_047416857.1XP_047272813.1  poly(A) RNA polymerase GLD2 isoform X6

    UniProtKB/TrEMBL
    D6RAF2
  4. XM_047416846.1XP_047272802.1  poly(A) RNA polymerase GLD2 isoform X2

  5. XM_011543220.4XP_011541522.1  poly(A) RNA polymerase GLD2 isoform X1

    See identical proteins and their annotated locations for XP_011541522.1

    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  6. XM_047416856.1XP_047272812.1  poly(A) RNA polymerase GLD2 isoform X6

    UniProtKB/TrEMBL
    D6RAF2
  7. XM_017009152.3XP_016864641.1  poly(A) RNA polymerase GLD2 isoform X2

    Conserved Domains (1) summary
    COG5260
    Location:154489
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  8. XM_047416859.1XP_047272815.1  poly(A) RNA polymerase GLD2 isoform X7

  9. XM_011543229.4XP_011541531.1  poly(A) RNA polymerase GLD2 isoform X5

    Conserved Domains (2) summary
    cd05402
    Location:176323
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    pfam03828
    Location:368422
    PAP_assoc; Cid1 family poly A polymerase
  10. XM_047416851.1XP_047272807.1  poly(A) RNA polymerase GLD2 isoform X3

    UniProtKB/Swiss-Prot
    Q8N927
  11. XM_047416853.1XP_047272809.1  poly(A) RNA polymerase GLD2 isoform X4

  12. XM_047416844.1XP_047272800.1  poly(A) RNA polymerase GLD2 isoform X1

  13. XM_047416852.1XP_047272808.1  poly(A) RNA polymerase GLD2 isoform X3

    UniProtKB/Swiss-Prot
    Q8N927
  14. XM_047416848.1XP_047272804.1  poly(A) RNA polymerase GLD2 isoform X2

  15. XM_047416854.1XP_047272810.1  poly(A) RNA polymerase GLD2 isoform X4

  16. XM_011543225.3XP_011541527.1  poly(A) RNA polymerase GLD2 isoform X1

    See identical proteins and their annotated locations for XP_011541527.1

    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  17. XM_047416858.1XP_047272814.1  poly(A) RNA polymerase GLD2 isoform X6

    UniProtKB/TrEMBL
    D6RAF2
  18. XM_047416863.1XP_047272819.1  poly(A) RNA polymerase GLD2 isoform X11

  19. XM_047416845.1XP_047272801.1  poly(A) RNA polymerase GLD2 isoform X1

  20. XM_047416849.1XP_047272805.1  poly(A) RNA polymerase GLD2 isoform X2

  21. XM_047416855.1XP_047272811.1  poly(A) RNA polymerase GLD2 isoform X4

  22. XM_011543224.3XP_011541526.1  poly(A) RNA polymerase GLD2 isoform X1

    See identical proteins and their annotated locations for XP_011541526.1

    Conserved Domains (1) summary
    COG5260
    Location:154493
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
  23. XM_047416847.1XP_047272803.1  poly(A) RNA polymerase GLD2 isoform X2

  24. XM_047416862.1XP_047272818.1  poly(A) RNA polymerase GLD2 isoform X10

  25. XM_047416860.1XP_047272816.1  poly(A) RNA polymerase GLD2 isoform X8

  26. XM_047416861.1XP_047272817.1  poly(A) RNA polymerase GLD2 isoform X9

  27. XM_047416864.1XP_047272820.1  poly(A) RNA polymerase GLD2 isoform X11

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    80096704..80172520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)