U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR7D2 olfactory receptor family 7 subfamily D member 2 [ Homo sapiens (human) ]

Gene ID: 162998, updated on 5-Aug-2022

Summary

Official Symbol
OR7D2provided by HGNC
Official Full Name
olfactory receptor family 7 subfamily D member 2provided by HGNC
Primary source
HGNC:HGNC:8378
See related
Ensembl:ENSG00000188000 AllianceGenome:HGNC:8378
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR19-4; OR19-10; HTPCRH03
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR7D2 in Genome Data Viewer
Location:
19p13.2
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9178979..9188818)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9305174..9315012)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9289655..9299494)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily G member 3 Neighboring gene zinc finger protein 317 Neighboring gene elongin C pseudogene 29 Neighboring gene olfactory receptor family 7 subfamily E member 16 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 25 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38149

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 7D2
Names
olfactory receptor 19-4
olfactory receptor OR19-10

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386112.1NP_001373041.1  olfactory receptor 7D2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC011464
    UniProtKB/Swiss-Prot
    Q8N133
    Related
    ENSP00000492939.1, ENST00000642043.1
    Conserved Domains (1) summary
    cd15234
    Location:25301
    7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_175883.4NP_787079.1  olfactory receptor 7D2

    See identical proteins and their annotated locations for NP_787079.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC011464
    Consensus CDS
    CCDS32900.1
    UniProtKB/Swiss-Prot
    Q8N133, Q96RA2
    Related
    ENSP00000493200.1, ENST00000641288.2
    Conserved Domains (1) summary
    cd15234
    Location:25301
    7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    9178979..9188818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438317.1XP_047294273.1  olfactory receptor 7D2 isoform X1

    UniProtKB/Swiss-Prot
    Q8N133

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    9305174..9315012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)