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ZNF296 zinc finger protein 296 [ Homo sapiens (human) ]

Gene ID: 162979, updated on 3-May-2020

Summary

Official Symbol
ZNF296provided by HGNC
Official Full Name
zinc finger protein 296provided by HGNC
Primary source
HGNC:HGNC:15981
See related
Ensembl:ENSG00000170684 MIM:613226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZFP296; ZNF342
Expression
Broad expression in bone marrow (RPKM 1.9), spleen (RPKM 1.8) and 18 other tissues See more
Orthologs

Genomic context

See ZNF296 in Genome Data Viewer
Location:
19q13.32
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (45071500..45076478, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45574758..45579688, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RELB proto-oncogene, NF-kB subunit Neighboring gene CLK4 associating serine/arginine rich protein Neighboring gene RNA, U6 small nuclear 611, pseudogene Neighboring gene gem nuclear organelle associated protein 7 Neighboring gene GEMIN7 antisense RNA 1 Neighboring gene protein phosphatase 1 regulatory subunit 37 Neighboring gene eukaryotic translation initiation factor 5A pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of dendrite development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 296
Names
zinc finger protein 342

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145288.3NP_660331.1  zinc finger protein 296

    See identical proteins and their annotated locations for NP_660331.1

    Status: VALIDATED

    Source sequence(s)
    BC019352, BF434185
    Consensus CDS
    CCDS12653.1
    UniProtKB/Swiss-Prot
    Q8WUU4
    Related
    ENSP00000302770.1, ENST00000303809.7
    Conserved Domains (5) summary
    sd00017
    Location:388408
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:233253
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:387408
    zf-C2H2; Zinc finger, C2H2 type
    pfam12756
    Location:387467
    zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    pfam13465
    Location:245270
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    45071500..45076478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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