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ELOA3P elongin A3, pseudogene [ Homo sapiens (human) ]

Gene ID: 162699, updated on 28-Oct-2024

Summary

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Official Symbol
ELOA3Pprovided by HGNC
Official Full Name
elongin A3, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:24617
See related
AllianceGenome:HGNC:24617
Gene type
pseudo
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ELOA3; ELOA3A; HsT829; TCEB3C; ELOA3AP; TCEB3L2
Summary
The SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This gene represents a likely pseudogene of ELOA (GeneID: 6924). [provided by RefSeq, Jun 2020]
Annotation information
not in current annotation release
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Genomic context

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See ELOA3P in Genome Data Viewer
Location:
18q21.1
Annotation release Status Assembly Chr Location
109.20211119 latest, but not current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (47028021..47030461, complement)

Bibliography

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Related articles in PubMed

  1. A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes. Strichman-Almashanu LZ, et al. Genome Res, 2002 Apr. PMID 11932239, Free PMC Article
  2. Identification and biochemical characterization of a novel transcription elongation factor, Elongin A3. Yamazaki K, et al. J Biol Chem, 2002 Jul 19. PMID 11994304
  3. Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics. Crockett DK, et al. Proteomics, 2005 Apr. PMID 15717329
  4. Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Ito T, et al. Nat Genet, 2021 Dec. PMID 34857952
  5. In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker. Gao H, et al. Anal Chem, 2022 May 31. PMID 35575683

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated 2012-02-22)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated 2012-02-22)

ClinGen Genome Curation Page

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • RNA polymerase II transcription factor SIII subunit A3
  • elongin A3 family member A
  • transcription elongation factor B polypeptide 3C (elongin A3)
  • transcription elongation factor B subunit 3C

NCBI Reference Sequences (RefSeq)

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Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_016749.1: Suppressed sequence

    Description
    NG_016749.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  2. NM_145653.3: Suppressed sequence

    Description
    NM_145653.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
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