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Rida reactive intermediate imine deaminase A homolog [ Mus musculus (house mouse) ]

Gene ID: 15473, updated on 12-May-2024

Summary

Official Symbol
Ridaprovided by MGI
Official Full Name
reactive intermediate imine deaminase A homologprovided by MGI
Primary source
MGI:MGI:1095401
See related
Ensembl:ENSMUSG00000022323 AllianceGenome:MGI:1095401
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HR12; HRP12; Hrsp12
Summary
Predicted to enable several functions, including 2-iminobutanoate deaminase activity; endoribonuclease activity, producing 3'-phosphomonoesters; and identical protein binding activity. Predicted to be involved in negative regulation of epithelial cell proliferation; negative regulation of gene expression; and organonitrogen compound catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human RIDA (reactive intermediate imine deaminase A homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 155.7), liver adult (RPKM 100.0) and 8 other tissues See more
Orthologs
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Genomic context

See Rida in Genome Data Viewer
Location:
15 B3.1; 15 14.34 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (34484168..34495392, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (34484022..34495246, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:34372917-34373070 Neighboring gene predicted gene, 24523 Neighboring gene ribosomal protein L30 Neighboring gene glutamate rich 5 Neighboring gene processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) Neighboring gene predicted gene, 22208

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 2-iminobutanoate deaminase activity ISO
Inferred from Sequence Orthology
more info
 
enables 2-iminobutanoate/2-iminopropanoate deaminase IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA endonuclease activity, producing 3'-phosphomonoesters ISO
Inferred from Sequence Orthology
more info
 
enables deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables ion binding ISO
Inferred from Sequence Orthology
more info
 
enables long-chain fatty acid binding ISO
Inferred from Sequence Orthology
more info
 
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables transition metal ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA destabilization ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of translation ISO
Inferred from Sequence Orthology
more info
 
involved_in organonitrogen compound catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in organonitrogen compound catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
2-iminobutanoate/2-iminopropanoate deaminase
Names
heat-responsive protein 12
ribonuclease UK114
translation inhibitor L-PSP ribonuclease
NP_032313.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008287.3NP_032313.2  2-iminobutanoate/2-iminopropanoate deaminase

    See identical proteins and their annotated locations for NP_032313.2

    Status: VALIDATED

    Source sequence(s)
    AW045776, BC125592, BU559752
    Consensus CDS
    CCDS27418.1
    UniProtKB/Swiss-Prot
    P52760, Q569N4
    Related
    ENSMUSP00000022946.6, ENSMUST00000022946.6
    Conserved Domains (1) summary
    TIGR00004
    Location:6129
    TIGR00004; reactive intermediate/imine deaminase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    34484168..34495392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)