Format

Send to:

Choose Destination

RIDA reactive intermediate imine deaminase A homolog [ Homo sapiens (human) ]

Gene ID: 10247, updated on 7-Dec-2018

Summary

Official Symbol
RIDAprovided by HGNC
Official Full Name
reactive intermediate imine deaminase A homologprovided by HGNC
Primary source
HGNC:HGNC:16897
See related
Ensembl:ENSG00000132541 MIM:602487
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PSP; P14.5; UK114; HRSP12; hp14.5
Expression
Biased expression in liver (RPKM 363.6), kidney (RPKM 202.2) and 3 other tissues See more
Orthologs

Genomic context

See RIDA in Genome Data Viewer
Location:
8q22.2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 8 NC_000008.11 (98102339..98117190, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (99114567..99129418, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 703, pseudogene Neighboring gene glutamate rich 5 Neighboring gene POP1 homolog, ribonuclease P/MRP subunit Neighboring gene uncharacterized LOC105375660 Neighboring gene RNA, U6 small nuclear 914, pseudogene Neighboring gene NIPA like domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
deaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
deaminase activity TAS
Traceable Author Statement
more info
 
endoribonuclease activity, producing 3'-phosphomonoesters ISS
Inferred from Sequence or Structural Similarity
more info
 
long-chain fatty acid binding IEA
Inferred from Electronic Annotation
more info
 
platinum binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 
xenon atom binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G1 to G0 transition IEA
Inferred from Electronic Annotation
more info
 
L-threonine catabolic process to glycine TAS
Traceable Author Statement
more info
 
RNA phosphodiester bond hydrolysis, endonucleolytic IEA
Inferred from Electronic Annotation
more info
 
brain development IEA
Inferred from Electronic Annotation
more info
 
kidney development IEA
Inferred from Electronic Annotation
more info
 
lung development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of translation ISS
Inferred from Sequence or Structural Similarity
more info
 
organonitrogen compound catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organonitrogen compound catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
response to lipid IEA
Inferred from Electronic Annotation
more info
 
response to salt IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
extracellular exosome HDA PubMed 
mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
2-iminobutanoate/2-iminopropanoate deaminase
Names
14.5 kDa translational inhibitor protein
UK114 antigen homolog
heat-responsive protein 12
perchloric acid-soluble protein
ribonuclease UK114
translation inhibitor L-PSP ribonuclease
translational inhibitor p14.5
translational inhibitor protein p14.5
NP_005827.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005836.3NP_005827.1  2-iminobutanoate/2-iminopropanoate deaminase

    See identical proteins and their annotated locations for NP_005827.1

    Status: VALIDATED

    Source sequence(s)
    BC012592, X95384
    Consensus CDS
    CCDS6276.1
    UniProtKB/Swiss-Prot
    P52758
    UniProtKB/TrEMBL
    A0A024R9H2
    Related
    ENSP00000254878.3, ENST00000254878.7
    Conserved Domains (1) summary
    TIGR00004
    Location:6129
    TIGR00004; reactive intermediate/imine deaminase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p12 Primary Assembly

    Range
    98102339..98117190 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center