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ZC2HC1B zinc finger C2HC-type containing 1B [ Homo sapiens (human) ]

Gene ID: 153918, updated on 5-Jul-2025
Official Symbol
ZC2HC1Bprovided by HGNC
Official Full Name
zinc finger C2HC-type containing 1Bprovided by HGNC
Primary source
HGNC:HGNC:21174
See related
Ensembl:ENSG00000118491 AllianceGenome:HGNC:21174
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf94; FAM164B; dJ468K18.5
Summary
Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Restricted expression toward testis (RPKM 7.2) See more
Orthologs
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See ZC2HC1B in Genome Data Viewer
Location:
6q24.2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (143864474..143938343)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (145057154..145131034)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (144185611..144259480)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene PHACTR2 antisense RNA 1 Neighboring gene phosphatase and actin regulator 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17630 Neighboring gene MPRA-validated peak6177 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:143958702-143959245 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr6:143998446-143999294 Neighboring gene MPRA-validated peak6179 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:144059920-144060420 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:144065167-144065836 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:144067178-144067848 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:144067849-144068518 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:144068519-144069188 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25204 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25206 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25205 Neighboring gene MPRA-validated peak6180 silencer Neighboring gene MPRA-validated peak6181 silencer Neighboring gene LTV1 ribosome biogenesis factor Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25207 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:144279682-144280240 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:144285771-144286284 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:144293958-144294542 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:144294543-144295127 Neighboring gene PLAG1 like zinc finger 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:144328825-144329007 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17632 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17633 Neighboring gene FKBP prolyl isomerase 7 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25208 Neighboring gene hydatidiform mole associated and imprinted

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Markers

Potential readthrough

Included gene: LTV1

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
zinc finger C2HC domain-containing protein 1B
Names
family with sequence similarity 164, member B
protein FAM164B

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013623.3NP_001013645.1  zinc finger C2HC domain-containing protein 1B

    See identical proteins and their annotated locations for NP_001013645.1

    Status: VALIDATED

    Source sequence(s)
    BC146950, DB515645
    Consensus CDS
    CCDS47495.1
    UniProtKB/Swiss-Prot
    B2RUZ7, Q5TFG8, Q5TFG9
    Related
    ENSP00000237275.6, ENST00000237275.9
    Conserved Domains (1) summary
    pfam13913
    Location:1438
    zf-C2HC_2; zinc-finger of a C2HC-type

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    143864474..143938343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    145057154..145131034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)