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LTV1 LTV1 ribosome biogenesis factor [ Homo sapiens (human) ]

Gene ID: 84946, updated on 5-Sep-2021

Summary

Official Symbol
LTV1provided by HGNC
Official Full Name
LTV1 ribosome biogenesis factorprovided by HGNC
Primary source
HGNC:HGNC:21173
See related
Ensembl:ENSG00000135521
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf93; dJ468K18.4
Expression
Ubiquitous expression in bone marrow (RPKM 17.0), testis (RPKM 13.5) and 25 other tissues See more
Orthologs
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Genomic context

See LTV1 in Genome Data Viewer
Location:
6q24.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (143843338..143863812)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (144164475..144184949)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378035 Neighboring gene PHACTR2 antisense RNA 1 Neighboring gene phosphatase and actin regulator 2 Neighboring gene zinc finger C2HC-type containing 1B Neighboring gene PLAG1 like zinc finger 1 Neighboring gene hydatidiform mole associated and imprinted

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14909, FLJ18519

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal small subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein LTV1 homolog
Names
LTV1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001329953.2NP_001316882.1  protein LTV1 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AL049844
  2. NM_032860.5NP_116249.2  protein LTV1 homolog isoform 1

    See identical proteins and their annotated locations for NP_116249.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AA453435, BC009855, DA885378
    Consensus CDS
    CCDS5201.1
    UniProtKB/Swiss-Prot
    Q96GA3
    Related
    ENSP00000356548.5, ENST00000367576.6
    Conserved Domains (1) summary
    pfam04180
    Location:15445
    LTV; Low temperature viability protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    143843338..143863812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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