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TMEM167A transmembrane protein 167A [ Homo sapiens (human) ]

Gene ID: 153339, updated on 21-Dec-2019

Summary

Official Symbol
TMEM167Aprovided by HGNC
Official Full Name
transmembrane protein 167Aprovided by HGNC
Primary source
HGNC:HGNC:28330
See related
Ensembl:ENSG00000174695
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMEM167
Expression
Ubiquitous expression in adrenal (RPKM 30.5), brain (RPKM 22.8) and 25 other tissues See more
Orthologs

Genomic context

See TMEM167A in Genome Data Viewer
Location:
5q14.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (83052846..83077394, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (82348665..82373272, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379051 Neighboring gene ST13, Hsp70 interacting protein pseudogene 12 Neighboring gene uncharacterized LOC105379052 Neighboring gene small Cajal body-specific RNA 18 Neighboring gene X-ray repair cross complementing 4 Neighboring gene ribosomal protein L13 pseudogene 9 Neighboring gene coenzyme Q10B pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
NHGRI GWA Catalog
Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30508, MGC23909, DKFZp686I1152

Gene Ontology Provided by GOA

Process Evidence Code Pubs
intracellular transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein kish-A
Names
transmembrane protein 167
NP_777569.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174909.5NP_777569.1  protein kish-A precursor

    See identical proteins and their annotated locations for NP_777569.1

    Status: VALIDATED

    Source sequence(s)
    AI799606, BC107575, BX647979, DA100343
    Consensus CDS
    CCDS34198.1
    UniProtKB/Swiss-Prot
    Q8TBQ9
    Related
    ENSP00000424707.1, ENST00000502346.2
    Conserved Domains (1) summary
    pfam06842
    Location:1044
    DUF1242; Protein of unknown function (DUF1242)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    83052846..83077394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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