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TEKT4 tektin 4 [ Homo sapiens (human) ]

Gene ID: 150483, updated on 17-Jun-2019

Summary

Official Symbol
TEKT4provided by HGNC
Official Full Name
tektin 4provided by HGNC
Primary source
HGNC:HGNC:31012
See related
Ensembl:ENSG00000163060
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 2.0), thyroid (RPKM 0.6) and 1 other tissue See more
Orthologs

Genomic context

See TEKT4 in Genome Data Viewer
Location:
2q11.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (94871430..94876823)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (95537188..95542568)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 20 family member A8, pseudogene Neighboring gene RNA, U6 small nuclear 1320, pseudogene Neighboring gene ankyrin repeat domain 57 pseudogene Neighboring gene uncharacterized LOC442028 Neighboring gene MT-CO3 pseudogene 45 Neighboring gene ribosomal protein S24 pseudogene 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC27019

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus HDA PubMed 
sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tektin-4
Names
epididymis secretory sperm binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286559.2NP_001273488.1  tektin-4 isoform 2

    See identical proteins and their annotated locations for NP_001273488.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site and initiates translation from a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC097374, AK097438
    Conserved Domains (1) summary
    pfam03148
    Location:2241
    Tektin; Tektin family
  2. NM_144705.4NP_653306.1  tektin-4 isoform 1

    See identical proteins and their annotated locations for NP_653306.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC097374, BC021716, BI832036
    Consensus CDS
    CCDS2005.1
    UniProtKB/Swiss-Prot
    Q8WW24
    Related
    ENSP00000295201.4, ENST00000295201.5
    Conserved Domains (1) summary
    pfam03148
    Location:44423
    Tektin; Tektin family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    94871430..94876823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510670.2XP_011508972.1  tektin-4 isoform X1

    Conserved Domains (1) summary
    pfam03148
    Location:44464
    Tektin; Tektin family
  2. XM_005263876.3XP_005263933.1  tektin-4 isoform X2

    Conserved Domains (1) summary
    pfam03148
    Location:44312
    Tektin; Tektin family
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