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Tekt4 tektin 4 [ Mus musculus (house mouse) ]

Gene ID: 71840, updated on 3-Apr-2024

Summary

Official Symbol
Tekt4provided by MGI
Official Full Name
tektin 4provided by MGI
Primary source
MGI:MGI:1919090
See related
Ensembl:ENSMUSG00000024175 AllianceGenome:MGI:1919090
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700010L19Rik
Summary
Acts upstream of or within cilium movement involved in cell motility and regulation of brood size. Located in sperm midpiece and sperm principal piece. Is expressed in choroid invagination; diencephalon roof plate; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human TEKT4 (tektin 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 138.3) See more
Orthologs
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Genomic context

See Tekt4 in Genome Data Viewer
Location:
17 A3.3; 17 12.6 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (25673511..25695576)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25454549..25476602)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene tryptase gamma 1 Neighboring gene calcium channel, voltage-dependent, T type, alpha 1H subunit Neighboring gene predicted gene, 33617 Neighboring gene STARR-seq mESC enhancer starr_42107 Neighboring gene somatostatin receptor 5 Neighboring gene predicted gene, 53993 Neighboring gene predicted gene, 33727

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC144759, MGC144760

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cilium movement involved in cell motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_positive_effect regulation of brood size IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in axonemal A tubule inner sheath IDA
Inferred from Direct Assay
more info
PubMed 
located_in axonemal microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 
located_in sperm midpiece IDA
Inferred from Direct Assay
more info
PubMed 
located_in sperm principal piece IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
tektin-4
Names
testicular microtubules-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418821.1NP_001405750.1  tektin-4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC131323
    UniProtKB/TrEMBL
    A0A3Q4EH78
    Related
    ENSMUSP00000157356.2, ENSMUST00000235033.3
  2. NM_001418822.1NP_001405751.1  tektin-4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC131323
    Related
    ENSMUSP00000159923.1, ENSMUST00000249765.1
  3. NM_027951.2NP_082227.1  tektin-4 isoform 1

    See identical proteins and their annotated locations for NP_082227.1

    Status: VALIDATED

    Source sequence(s)
    AC131323
    Consensus CDS
    CCDS28519.1
    UniProtKB/Swiss-Prot
    A0A0R4J051, Q149S1, Q3ZTL6, Q9DAH3
    UniProtKB/TrEMBL
    A0A3Q4EGQ7
    Related
    ENSMUSP00000025002.2, ENSMUST00000025002.4
    Conserved Domains (1) summary
    pfam03148
    Location:56434
    Tektin; Tektin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    25673511..25695576
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524948.3XP_006525011.1  tektin-4 isoform X1

    Conserved Domains (1) summary
    pfam03148
    Location:46305
    Tektin; Tektin family