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Gsg1 germ cell associated 1 [ Mus musculus (house mouse) ]

Gene ID: 14840, updated on 8-Feb-2024

Summary

Official Symbol
Gsg1provided by MGI
Official Full Name
germ cell associated 1provided by MGI
Primary source
MGI:MGI:1194499
See related
Ensembl:ENSMUSG00000030206 AllianceGenome:MGI:1194499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables RNA polymerase binding activity. Located in endoplasmic reticulum. Orthologous to human GSG1 (germ cell associated 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 1505.6) See more
Orthologs
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Genomic context

See Gsg1 in Genome Data Viewer
Location:
6 G1; 6 66.07 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (135214327..135231334, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (135237329..135254336, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19434 Neighboring gene predicted gene, 36533 Neighboring gene family with sequence similarity 234, member B Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:135168385-135168675 Neighboring gene predicted gene, 57750 Neighboring gene STARR-seq mESC enhancer starr_17565 Neighboring gene predicted gene, 36640 Neighboring gene STARR-seq mESC enhancer starr_17566 Neighboring gene predicted gene, 36582 Neighboring gene phosphatidylethanolamine binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
germ cell-specific gene 1 protein
Names
germ cell-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080552.1NP_001074021.1  germ cell-specific gene 1 protein isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    BC023009
    Consensus CDS
    CCDS39682.1
    UniProtKB/Swiss-Prot
    Q8C2N5, Q8R1W2, Q9D9Z3, Q9Z1H7
    Related
    ENSMUSP00000085022.6, ENSMUST00000087729.12
    Conserved Domains (1) summary
    pfam07803
    Location:13125
    GSG-1; GSG1-like protein
  2. NM_001080553.1NP_001074022.1  germ cell-specific gene 1 protein isoform b

    See identical proteins and their annotated locations for NP_001074022.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    BC023009, BY098420
    Consensus CDS
    CCDS39683.1
    UniProtKB/TrEMBL
    E9QQ16
    Related
    ENSMUSP00000107541.2, ENSMUST00000111910.4
    Conserved Domains (1) summary
    pfam07803
    Location:10122
    GSG-1; GSG1-like protein
  3. NM_010352.2NP_034482.2  germ cell-specific gene 1 protein isoform b

    See identical proteins and their annotated locations for NP_034482.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    BC023009, BY098420, CA465575
    Consensus CDS
    CCDS39683.1
    UniProtKB/TrEMBL
    E9QQ16
    Related
    ENSMUSP00000107542.3, ENSMUST00000111911.9
    Conserved Domains (1) summary
    pfam07803
    Location:10122
    GSG-1; GSG1-like protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    135214327..135231334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)