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ZNF542P zinc finger protein 542, pseudogene [ Homo sapiens (human) ]

Gene ID: 147947, updated on 5-Sep-2025
Official Symbol
ZNF542Pprovided by HGNC
Official Full Name
zinc finger protein 542, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:25393
See related
Ensembl:ENSG00000290720 AllianceGenome:HGNC:25393
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF542
Summary
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in thyroid (RPKM 6.2), testis (RPKM 5.6) and 25 other tissues See more
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See ZNF542P in Genome Data Viewer
Location:
19q13.43
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56368099..56379828)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59462491..59474231)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56879468..56891197)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger and SCAN domain containing 5A Neighboring gene ZSCAN5A antisense RNA 1 Neighboring gene NDUFAF1 pseudogene 1 Neighboring gene vomeronasal 2 receptor 18 pseudogene Neighboring gene Sharpr-MPRA regulatory region 13801 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15118 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56888366-56889565 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56895030-56896229 Neighboring gene SLC25A36 pseudogene 1 Neighboring gene zinc finger protein 582 Neighboring gene ZNF582 divergent transcript

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. ZNF542P is a pseudogene associated with LDL response to simvastatin treatment. Kim K, et al. Sci Rep, 2018 Aug 20. PMID 30127457, Free PMC Article
  2. Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC). Pu W, et al. Clin Epigenetics, 2017. PMID 29270239, Free PMC Article
  3. A GO catalogue of human DNA-binding transcription factors. Lovering RC, et al. Biochim Biophys Acta Gene Regul Mech, 2021 Nov-Dec. PMID 34673265
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A role for ZNF542P in LDLC response to simvastatin.
    Title: ZNF542P is a pseudogene associated with LDL response to simvastatin treatment.
  2. Integration analysis of esophageal squamous cell carcinoma (ESCC) identified five hyper-methylated CpG sites in STK3, ZNF418 and ZNF542 that can be used for effective methylation-based testing for ESCC diagnosis.
    Title: Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).
Submit: New GeneRIF Correction

Review eQTL and phenotype association data in this region using PheGenI

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Markers

Other Names

  • zinc finger protein pseudogene

Clone Names

  • DKFZp686B2197, DKFZp686I1219

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003127.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has an alternate first exon, includes an additional internal exon in the 5' region, and uses an alternate splice site in an internal exon in the 3' region, compared to variant 1.
    Source sequence(s)
    AC006116, BC089419, BX640680, DB051263
    Related
    ENST00000467807.5

  2. NR_024055.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has an alternate first exon, includes an additional internal exon in the 5' region, and lacks an internal exon in the 3' region, compared to variant 1.
    Source sequence(s)
    AC006116, DA095148

  3. NR_024056.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in an internal exon in the 3' region, compared to variant 1.
    Source sequence(s)
    AC006116, BC089419, BX647919, DA095148, DA311525

  4. NR_024057.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate internal exon in the 3' region, compared to variant 1.
    Source sequence(s)
    AC006116, BC089419, DA095148, DA311525
    Related
    ENST00000495307.5

  5. NR_033418.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AC006116, BC064603, BC089419, DA095148, DA311525
    Related
    ENST00000490123.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    56368099..56379828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    59462491..59474231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_194319.1: Suppressed sequence

    Description
    NM_194319.1: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5EBM4.2 GenPept UniProtKB/Swiss-Prot:Q5EBM4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials