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Gng7 guanine nucleotide binding protein (G protein), gamma 7 [ Mus musculus (house mouse) ]

Gene ID: 14708, updated on 8-Feb-2024

Summary

Official Symbol
Gng7provided by MGI
Official Full Name
guanine nucleotide binding protein (G protein), gamma 7provided by MGI
Primary source
MGI:MGI:95787
See related
Ensembl:ENSMUSG00000048240 AllianceGenome:MGI:95787
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hg3b
Summary
Predicted to enable G-protein beta-subunit binding activity. Involved in regulation of adenylate cyclase activity. Acts upstream of or within behavioral fear response; locomotory behavior; and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in central nervous system; early conceptus; oocyte; and retina. Orthologous to human GNG7 (G protein subunit gamma 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 23.8), frontal lobe adult (RPKM 19.7) and 12 other tissues See more
Orthologs
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Genomic context

See Gng7 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80784463..80850742, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80948624..81014925, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene lamin B2 Neighboring gene STARR-positive B cell enhancer ABC_E721 Neighboring gene growth arrest and DNA-damage-inducible 45 beta Neighboring gene STARR-seq mESC enhancer starr_27304 Neighboring gene ATP synthase subunit f, mitochondrial-like Neighboring gene STARR-seq mESC enhancer starr_27308 Neighboring gene STARR-seq mESC enhancer starr_27310 Neighboring gene STARR-positive B cell enhancer ABC_E2951 Neighboring gene STARR-positive B cell enhancer ABC_E1807 Neighboring gene STARR-positive B cell enhancer ABC_E10629 Neighboring gene DIRAS family, GTP-binding RAS-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E2952 Neighboring gene predicted gene 16099 Neighboring gene solute carrier family 39 (zinc transporter), member 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta-subunit binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Names
guanine nucleotide binding protein (G protein), gamma 7 subunit
heterotrimeric guanine nucleotide-binding protein 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001038655.2NP_001033744.2  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

    Status: VALIDATED

    Source sequence(s)
    AC152500
    Consensus CDS
    CCDS24039.1
    UniProtKB/Swiss-Prot
    Q61016, Q8JZP6
    UniProtKB/TrEMBL
    Q3UGN1
    Related
    ENSMUSP00000114003.2, ENSMUST00000118233.8
  2. NM_001406263.1NP_001393192.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

    Status: VALIDATED

    Source sequence(s)
    AC152500
    UniProtKB/Swiss-Prot
    Q61016, Q8JZP6
    UniProtKB/TrEMBL
    Q3UGN1
  3. NM_001406264.1NP_001393193.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

    Status: VALIDATED

    Source sequence(s)
    AC152500
    UniProtKB/Swiss-Prot
    Q61016, Q8JZP6
    UniProtKB/TrEMBL
    Q3UGN1
  4. NM_010319.4NP_034449.3  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

    Status: VALIDATED

    Source sequence(s)
    AC152500
    Consensus CDS
    CCDS24039.1
    UniProtKB/Swiss-Prot
    Q61016, Q8JZP6
    UniProtKB/TrEMBL
    Q3UGN1
    Related
    ENSMUSP00000112409.2, ENSMUST00000117805.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    80784463..80850742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)