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Gng5 guanine nucleotide binding protein (G protein), gamma 5 [ Mus musculus (house mouse) ]

Gene ID: 14707, updated on 26-Sep-2020

Summary

Official Symbol
Gng5provided by MGI
Official Full Name
guanine nucleotide binding protein (G protein), gamma 5provided by MGI
Primary source
MGI:MGI:109164
See related
Ensembl:ENSMUSG00000068523
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G(y)5
Expression
Ubiquitous expression in placenta adult (RPKM 121.2), testis adult (RPKM 120.0) and 28 other tissues See more
Orthologs

Genomic context

See Gng5 in Genome Data Viewer
Location:
3; 3 H2
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (146205591..146211298)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (146499836..146505543)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (146162800..146168507)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene synovial sarcoma, X 2 interacting protein Neighboring gene chitobiase Neighboring gene spermatogenesis associated 1 Neighboring gene ribosome production factor 1 homolog Neighboring gene deoxyribonuclease II beta Neighboring gene urate oxidase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
PDZ domain binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of secondary heart field cardioblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
G-protein beta/gamma-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein beta/gamma-subunit complex ISO
Inferred from Sequence Orthology
more info
PubMed 
heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Names
guanine nucleotide binding protein (G protein), gamma 5 subunit
NP_034448.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010318.2NP_034448.2  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

    See identical proteins and their annotated locations for NP_034448.2

    Status: VALIDATED

    Source sequence(s)
    AK146065, BY132164
    Consensus CDS
    CCDS17903.1
    UniProtKB/Swiss-Prot
    Q80SZ7
    UniProtKB/TrEMBL
    Q3UKC8
    Related
    ENSMUSP00000087485.5, ENSMUST00000090031.11
    Conserved Domains (1) summary
    cd00068
    Location:763
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    146205591..146211298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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