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ST13P4 ST13, Hsp70 interacting protein pseudogene 4 [ Homo sapiens (human) ]

Gene ID: 145165, updated on 2-Nov-2024

Summary

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Official Symbol
ST13P4provided by HGNC
Official Full Name
ST13, Hsp70 interacting protein pseudogene 4provided by HGNC
Primary source
HGNC:HGNC:18487
See related
AllianceGenome:HGNC:18487
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM10A4; FAM10A4P
Summary
Predicted to enable protein dimerization activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ST13P4 in Genome Data Viewer
Location:
13q14.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (50172018..50173616)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (49392601..49394199)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (50746154..50747752)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene deleted in lymphocytic leukemia 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7759 Neighboring gene Sharpr-MPRA regulatory region 84 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5353 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:50656434-50657229 Neighboring gene microRNA 15a Neighboring gene NANOG hESC enhancer GRCh37_chr13:50695956-50696481 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5354 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5355 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5356 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:50699798-50700508 Neighboring gene ribosomal protein L18 pseudogene 10 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5358 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5359 Neighboring gene deleted in lymphocytic leukemia 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:50715020-50715693 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7760 Neighboring gene uncharacterized LOC124900337 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr13:50818353-50819552 Neighboring gene NANOG hESC enhancer GRCh37_chr13:50823191-50823706 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:50850586-50851108 Neighboring gene ribosomal protein L34 pseudogene 26

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer. Sossey-Alaoui K, et al. Genomics, 2002 Jul. PMID 12079276
  2. Phosphoproteomic analysis of the human pituitary. Beranova-Giorgianni S, et al. Pituitary, 2006. PMID 16807684
  3. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells. Russo LC, et al. J Proteomics, 2017 Jan 16. PMID 27371349
  4. Multiple common variants for celiac disease influencing immune gene expression. Dubois PC, et al. Nat Genet, 2010 Apr. PMID 20190752, Free PMC Article
  5. Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1. Luciano AK, et al. J Biol Chem, 2022 Oct. PMID 35973513, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. establishement of conditions to specifically undertake mutation studies of this chromosome 13 member
    Title: Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • ST13-like tumor suppressor
  • family with sequence similarity 10, member A4 pseudogene
  • suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular exosome HDA PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002183.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AF539468

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    50172018..50173616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    49392601..49394199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_153290.1: Suppressed sequence

    Description
    NM_153290.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IZP2.1 GenPept UniProtKB/Swiss-Prot:Q8IZP2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials