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XRRA1 X-ray radiation resistance associated 1 [ Homo sapiens (human) ]

Gene ID: 143570, updated on 2-Nov-2024

Summary

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Official Symbol
XRRA1provided by HGNC
Official Full Name
X-ray radiation resistance associated 1provided by HGNC
Primary source
HGNC:HGNC:18868
See related
Ensembl:ENSG00000166435 MIM:609788; AllianceGenome:HGNC:18868
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Involved in response to X-ray. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis (RPKM 10.6), thyroid (RPKM 6.1) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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See XRRA1 in Genome Data Viewer
Location:
11q13.4
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (74840910..74949091, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (74770425..74878625, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (74551955..74660136, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr11:74459725-74459945 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:74460158-74460751 Neighboring gene RNF169 intron CAGE-defined mid-level expression enhancer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:74466374-74466995 Neighboring gene ribosomal protein S12 pseudogene 22 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3758 Neighboring gene ring finger protein 169 Neighboring gene uncharacterized LOC124902715 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:74523526-74523714 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:74554898-74556097 Neighboring gene RNA, 7SL, cytoplasmic 239, pseudogene Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:74593699-74594283 Neighboring gene uncharacterized LOC107984352 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:74644275-74644750 Neighboring gene ribosomal protein L31 pseudogene 46 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:74659504-74660358 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:74660359-74661213 Neighboring gene signal peptidase complex subunit 2 Neighboring gene RNA, U6 small nuclear 216, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5260 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5261 Neighboring gene neuraminidase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Diesel exhaust particles disturb gene expression in mouse testis. Mori T, et al. Environ Toxicol, 2007 Feb. PMID 17295261
  2. Genetic architecture of asthma in African American patients. Chang X, et al. J Allergy Clin Immunol, 2023 Apr. PMID 36089080, Free PMC Article
  3. XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer. Wang W, et al. Biomed Res Int, 2017. PMID 29082250, Free PMC Article
  4. Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis. Mesak FM, et al. BMC Genomics, 2003 Aug 9. PMID 12908878, Free PMC Article
  5. A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Yao Z, et al. Mol Cell, 2017 Jan 19. PMID 28065597, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genetic architecture of asthma in African American patients.
    Title: Genetic architecture of asthma in African American patients.
  2. our results identify a novel link between XRRA1 and the ATM/CHK1/2 pathway and suggest that XRRA1 is involved in a DNA damage response that drives radio- and chemoresistance by regulating the ATM/CHK1/2 pathway.
    Title: XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer.
  3. Molecular cloning and gene expression patterns of XRRA1.
    Title: Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in response to X-ray IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear body IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
X-ray radiation resistance-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270380.3 → NP_001257309.1  X-ray radiation resistance-associated protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001257309.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple exons in the 3' coding region, compared to variant, which results in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AP000560, AP001992
    Consensus CDS
    CCDS58160.1
    UniProtKB/Swiss-Prot
    Q6P2D8
    UniProtKB/TrEMBL
    Q8TEH2
    Related
    ENSP00000435838.1, ENST00000527087.5
    Conserved Domains (3) summary
    cd00116
    Location:134 → 265
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:142 → 164
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:140 → 199
    LRR_8; Leucine rich repeat

  2. NM_001270381.3 → NP_001257310.1  X-ray radiation resistance-associated protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at an in-frame downstream start codon, compared to variant 1. The encoded protein (isoform 3) is shorter than isoform 1.
    Source sequence(s)
    AP000560, AP001992
    Consensus CDS
    CCDS58159.1
    UniProtKB/Swiss-Prot
    Q6P2D8
    UniProtKB/TrEMBL
    Q8TEH2
    Related
    ENSP00000319303.8, ENST00000321448.12

  3. NM_001378157.1 → NP_001365086.1  X-ray radiation resistance-associated protein 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4).
    Source sequence(s)
    AP000560, AP001992
    Consensus CDS
    CCDS91535.1
    UniProtKB/TrEMBL
    A0A804HIK0, A0A994J5L1
    Related
    ENSP00000507107.1, ENST00000684022.1
    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  4. NM_001378158.1 → NP_001365087.1  X-ray radiation resistance-associated protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  5. NM_001378159.1 → NP_001365088.1  X-ray radiation resistance-associated protein 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  6. NM_001378160.1 → NP_001365089.1  X-ray radiation resistance-associated protein 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  7. NM_001378161.1 → NP_001365090.1  X-ray radiation resistance-associated protein 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  8. NM_001378162.1 → NP_001365091.1  X-ray radiation resistance-associated protein 1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    Q8TEH2

  9. NM_001378163.1 → NP_001365092.1  X-ray radiation resistance-associated protein 1 isoform 10

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variant 11, encodes isoform 10.
    Source sequence(s)
    AP000560, AP001992

  10. NM_001378164.1 → NP_001365093.1  X-ray radiation resistance-associated protein 1 isoform 10

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variant 10, encodes isoform 10.
    Source sequence(s)
    AP000560, AP001992

  11. NM_001378165.1 → NP_001365094.1  X-ray radiation resistance-associated protein 1 isoform 11

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 13 and 14, encodes isoform 11.
    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    Q8TEH2

  12. NM_001378166.1 → NP_001365095.1  X-ray radiation resistance-associated protein 1 isoform 11

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13), as well as variants 12 and 14, encodes isoform 11.
    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    Q8TEH2

  13. NM_001378167.1 → NP_001365096.1  X-ray radiation resistance-associated protein 1 isoform 11

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14), as well as variants 12 and 13, encodes isoform 11.
    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    Q8TEH2

  14. NM_001378168.1 → NP_001365097.1  X-ray radiation resistance-associated protein 1 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  15. NM_001378169.1 → NP_001365098.1  X-ray radiation resistance-associated protein 1 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    UniProtKB/TrEMBL
    Q8TEH2

  16. NM_001378170.1 → NP_001365099.1  X-ray radiation resistance-associated protein 1 isoform 14

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17), as well as variant 18, encodes isoform 14.
    Source sequence(s)
    AP000560, AP001992

  17. NM_001378171.1 → NP_001365100.1  X-ray radiation resistance-associated protein 1 isoform 14

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18), as well as variant 17, encodes isoform 14.
    Source sequence(s)
    AP000560, AP001992

  18. NM_001378172.1 → NP_001365101.1  X-ray radiation resistance-associated protein 1 isoform 15

    Status: VALIDATED

    Description
    Transcript Variant: This variant (19), as well as variant 20, encodes isoform 15.
    Source sequence(s)
    AP000560, AP001992

  19. NM_001378173.1 → NP_001365102.1  X-ray radiation resistance-associated protein 1 isoform 15

    Status: VALIDATED

    Description
    Transcript Variant: This variant (20), as well as variant 19, encodes isoform 15.
    Source sequence(s)
    AP000560, AP001992

  20. NM_001378174.1 → NP_001365103.1  X-ray radiation resistance-associated protein 1 isoform 16

    Status: VALIDATED

    Description
    Transcript Variant: This variant (21), as well as variants 22 and 23, encodes isoform 16.
    Source sequence(s)
    AP000560, AP001992

  21. NM_001378175.1 → NP_001365104.1  X-ray radiation resistance-associated protein 1 isoform 16

    Status: VALIDATED

    Description
    Transcript Variant: This variant (22), as well as variants 21 and 23, encodes isoform 16.
    Source sequence(s)
    AP000560, AP001992

  22. NM_001378176.1 → NP_001365105.1  X-ray radiation resistance-associated protein 1 isoform 16

    Status: VALIDATED

    Description
    Transcript Variant: This variant (23), as well as variants 21 and 22, encodes isoform 16.
    Source sequence(s)
    AP000560, AP001992

  23. NM_182969.4 → NP_892014.1  X-ray radiation resistance-associated protein 1 isoform 1

    See identical proteins and their annotated locations for NP_892014.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AP000560, AP001992
    Consensus CDS
    CCDS44680.1
    UniProtKB/Swiss-Prot
    B5MD90, J3KNJ1, Q6P2D8, Q7RTT7, Q7Z463, Q7Z4U0
    UniProtKB/TrEMBL
    A0A994J5L1
    Related
    ENSP00000339918.6, ENST00000340360.10
    Conserved Domains (3) summary
    cd00116
    Location:134 → 265
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:142 → 164
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:140 → 199
    LRR_8; Leucine rich repeat

RNA

  1. NR_165434.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  2. NR_165435.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  3. NR_165436.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992
    Related
    ENST00000531849.5

  4. NR_165437.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  5. NR_165438.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

  6. NR_165439.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000560, AP001992

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    74840910..74949091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426407.1 → XP_047282363.1  X-ray radiation resistance-associated protein 1 isoform X28

  2. XM_047426401.1 → XP_047282357.1  X-ray radiation resistance-associated protein 1 isoform X22

  3. XM_047426404.1 → XP_047282360.1  X-ray radiation resistance-associated protein 1 isoform X25

  4. XM_047426392.1 → XP_047282348.1  X-ray radiation resistance-associated protein 1 isoform X13

  5. XM_047426396.1 → XP_047282352.1  X-ray radiation resistance-associated protein 1 isoform X25

  6. XM_011544765.2 → XP_011543067.1  X-ray radiation resistance-associated protein 1 isoform X13

    See identical proteins and their annotated locations for XP_011543067.1

  7. XM_047426406.1 → XP_047282362.1  X-ray radiation resistance-associated protein 1 isoform X28

  8. XM_047426399.1 → XP_047282355.1  X-ray radiation resistance-associated protein 1 isoform X22

  9. XM_047426408.1 → XP_047282364.1  X-ray radiation resistance-associated protein 1 isoform X29

  10. XM_047426402.1 → XP_047282358.1  X-ray radiation resistance-associated protein 1 isoform X25

  11. XM_047426405.1 → XP_047282361.1  X-ray radiation resistance-associated protein 1 isoform X26

  12. XM_047426394.1 → XP_047282350.1  X-ray radiation resistance-associated protein 1 isoform X23

  13. XM_047426388.1 → XP_047282344.1  X-ray radiation resistance-associated protein 1 isoform X13

  14. XM_047426393.1 → XP_047282349.1  X-ray radiation resistance-associated protein 1 isoform X22

  15. XM_047426395.1 → XP_047282351.1  X-ray radiation resistance-associated protein 1 isoform X25

  16. XM_047426400.1 → XP_047282356.1  X-ray radiation resistance-associated protein 1 isoform X26

  17. XM_047426391.1 → XP_047282347.1  X-ray radiation resistance-associated protein 1 isoform X21

  18. XM_017017228.3 → XP_016872717.1  X-ray radiation resistance-associated protein 1 isoform X24

  19. XM_005273770.3 → XP_005273827.1  X-ray radiation resistance-associated protein 1 isoform X13

    See identical proteins and their annotated locations for XP_005273827.1

  20. XM_047426397.1 → XP_047282353.1  X-ray radiation resistance-associated protein 1 isoform X23

  21. XM_047426387.1 → XP_047282343.1  X-ray radiation resistance-associated protein 1 isoform X17

  22. XM_011544761.2 → XP_011543063.1  X-ray radiation resistance-associated protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (2) summary
    COG4886
    Location:95 → 196
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:95 → 115
    LRR_1; leucine-rich repeat [structural motif]

  23. XM_011544759.2 → XP_011543061.1  X-ray radiation resistance-associated protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (3) summary
    cd00116
    Location:105 → 208
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:110 → 131
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:130 → 208
    LRR_8; Leucine rich repeat

  24. XM_047426382.1 → XP_047282338.1  X-ray radiation resistance-associated protein 1 isoform X9

  25. XM_047426384.1 → XP_047282340.1  X-ray radiation resistance-associated protein 1 isoform X12

  26. XM_047426390.1 → XP_047282346.1  X-ray radiation resistance-associated protein 1 isoform X20

  27. XM_047426383.1 → XP_047282339.1  X-ray radiation resistance-associated protein 1 isoform X11

  28. XM_011544758.2 → XP_011543060.1  X-ray radiation resistance-associated protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (3) summary
    cd00116
    Location:119 → 216
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:117 → 139
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:138 → 216
    LRR_8; Leucine rich repeat

  29. XM_017017224.3 → XP_016872713.1  X-ray radiation resistance-associated protein 1 isoform X18

    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  30. XM_011544762.2 → XP_011543064.1  X-ray radiation resistance-associated protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (3) summary
    cd00116
    Location:142 → 273
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:148 → 207
    LRR_8; Leucine rich repeat

  31. XM_047426386.1 → XP_047282342.1  X-ray radiation resistance-associated protein 1 isoform X16

  32. XM_011544757.2 → XP_011543059.1  X-ray radiation resistance-associated protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (3) summary
    cd00116
    Location:142 → 273
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:148 → 207
    LRR_8; Leucine rich repeat

  33. XM_017017222.3 → XP_016872711.1  X-ray radiation resistance-associated protein 1 isoform X14

  34. XM_011544756.2 → XP_011543058.1  X-ray radiation resistance-associated protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (3) summary
    cd00116
    Location:142 → 273
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:148 → 207
    LRR_8; Leucine rich repeat

  35. XM_017017221.2 → XP_016872710.1  X-ray radiation resistance-associated protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A994J5L1

  36. XM_011544755.2 → XP_011543057.1  X-ray radiation resistance-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A994J5L1
    Conserved Domains (2) summary
    COG4886
    Location:116 → 320
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]

  37. XM_011544763.3 → XP_011543065.1  X-ray radiation resistance-associated protein 1 isoform X10

    Conserved Domains (3) summary
    cd00116
    Location:142 → 273
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 172
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:148 → 207
    LRR_8; Leucine rich repeat

  38. XM_047426403.1 → XP_047282359.1  X-ray radiation resistance-associated protein 1 isoform X27

  39. XM_047426389.1 → XP_047282345.1  X-ray radiation resistance-associated protein 1 isoform X19

  40. XM_047426385.1 → XP_047282341.1  X-ray radiation resistance-associated protein 1 isoform X15

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    74770425..74878625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054367745.1 → XP_054223720.1  X-ray radiation resistance-associated protein 1 isoform X28

  2. XM_054367739.1 → XP_054223714.1  X-ray radiation resistance-associated protein 1 isoform X22

  3. XM_054367742.1 → XP_054223717.1  X-ray radiation resistance-associated protein 1 isoform X25

  4. XM_054367730.1 → XP_054223705.1  X-ray radiation resistance-associated protein 1 isoform X13

  5. XM_054367735.1 → XP_054223710.1  X-ray radiation resistance-associated protein 1 isoform X25

  6. XM_054367721.1 → XP_054223696.1  X-ray radiation resistance-associated protein 1 isoform X13

  7. XM_054367744.1 → XP_054223719.1  X-ray radiation resistance-associated protein 1 isoform X28

  8. XM_054367737.1 → XP_054223712.1  X-ray radiation resistance-associated protein 1 isoform X22

  9. XM_054367746.1 → XP_054223721.1  X-ray radiation resistance-associated protein 1 isoform X29

  10. XM_054367740.1 → XP_054223715.1  X-ray radiation resistance-associated protein 1 isoform X25

  11. XM_054367743.1 → XP_054223718.1  X-ray radiation resistance-associated protein 1 isoform X26

  12. XM_054367732.1 → XP_054223707.1  X-ray radiation resistance-associated protein 1 isoform X23

  13. XM_054367726.1 → XP_054223701.1  X-ray radiation resistance-associated protein 1 isoform X13

  14. XM_054367731.1 → XP_054223706.1  X-ray radiation resistance-associated protein 1 isoform X22

  15. XM_054367734.1 → XP_054223709.1  X-ray radiation resistance-associated protein 1 isoform X25

  16. XM_054367738.1 → XP_054223713.1  X-ray radiation resistance-associated protein 1 isoform X26

  17. XM_054367729.1 → XP_054223704.1  X-ray radiation resistance-associated protein 1 isoform X21

  18. XM_054367733.1 → XP_054223708.1  X-ray radiation resistance-associated protein 1 isoform X24

  19. XM_054367719.1 → XP_054223694.1  X-ray radiation resistance-associated protein 1 isoform X13

  20. XM_054367736.1 → XP_054223711.1  X-ray radiation resistance-associated protein 1 isoform X23

  21. XM_054367724.1 → XP_054223699.1  X-ray radiation resistance-associated protein 1 isoform X17

  22. XM_054367713.1 → XP_054223688.1  X-ray radiation resistance-associated protein 1 isoform X7

  23. XM_054367711.1 → XP_054223686.1  X-ray radiation resistance-associated protein 1 isoform X5

  24. XM_054367715.1 → XP_054223690.1  X-ray radiation resistance-associated protein 1 isoform X9

  25. XM_054367718.1 → XP_054223693.1  X-ray radiation resistance-associated protein 1 isoform X12

  26. XM_054367728.1 → XP_054223703.1  X-ray radiation resistance-associated protein 1 isoform X20

  27. XM_054367717.1 → XP_054223692.1  X-ray radiation resistance-associated protein 1 isoform X11

  28. XM_054367709.1 → XP_054223684.1  X-ray radiation resistance-associated protein 1 isoform X4

  29. XM_054367725.1 → XP_054223700.1  X-ray radiation resistance-associated protein 1 isoform X18

  30. XM_054367714.1 → XP_054223689.1  X-ray radiation resistance-associated protein 1 isoform X8

  31. XM_054367723.1 → XP_054223698.1  X-ray radiation resistance-associated protein 1 isoform X16

  32. XM_054367710.1 → XP_054223685.1  X-ray radiation resistance-associated protein 1 isoform X3

  33. XM_054367720.1 → XP_054223695.1  X-ray radiation resistance-associated protein 1 isoform X14

  34. XM_054367708.1 → XP_054223683.1  X-ray radiation resistance-associated protein 1 isoform X2

  35. XM_054367712.1 → XP_054223687.1  X-ray radiation resistance-associated protein 1 isoform X6

  36. XM_054367707.1 → XP_054223682.1  X-ray radiation resistance-associated protein 1 isoform X1

  37. XM_054367716.1 → XP_054223691.1  X-ray radiation resistance-associated protein 1 isoform X10

  38. XM_054367741.1 → XP_054223716.1  X-ray radiation resistance-associated protein 1 isoform X27

  39. XM_054367727.1 → XP_054223702.1  X-ray radiation resistance-associated protein 1 isoform X19

  40. XM_054367722.1 → XP_054223697.1  X-ray radiation resistance-associated protein 1 isoform X15

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P2D8.2 GenPept UniProtKB/Swiss-Prot:Q6P2D8

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