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NANP N-acetylneuraminic acid phosphatase [ Homo sapiens (human) ]

Gene ID: 140838, updated on 11-Sep-2019

Summary

Official Symbol
NANPprovided by HGNC
Official Full Name
N-acetylneuraminic acid phosphataseprovided by HGNC
Primary source
HGNC:HGNC:16140
See related
Ensembl:ENSG00000170191 MIM:610763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HDHD4; C20orf147; dJ694B14.3
Expression
Ubiquitous expression in adrenal (RPKM 2.0), testis (RPKM 1.9) and 25 other tissues See more
Orthologs

Genomic context

See NANP in Genome Data Viewer
Location:
20p11.21
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (25612935..25624014, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (25593571..25604648, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ninein like Neighboring gene RNA, U6atac small nuclear 17, pseudogene Neighboring gene ZNF337 antisense RNA 1 Neighboring gene RNA, 7SL, cytoplasmic 594, pseudogene Neighboring gene mediator complex subunit 28 pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC26833

Gene Ontology Provided by GOA

Function Evidence Code Pubs
N-acylneuraminate-9-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
N-acetylglucosamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
N-acetylneuraminate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
N-acylneuraminate-9-phosphatase
Names
Neu5Ac-9-Pase
haloacid dehalogenase-like hydrolase domain containing 4
haloacid dehalogenase-like hydrolase domain-containing protein 4
NP_689880.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152667.3NP_689880.1  N-acylneuraminate-9-phosphatase

    See identical proteins and their annotated locations for NP_689880.1

    Status: VALIDATED

    Source sequence(s)
    AI693731, AL031673, AL833116, BC022552, CF126993, DA858639
    Consensus CDS
    CCDS13173.1
    UniProtKB/Swiss-Prot
    Q8TBE9
    Related
    ENSP00000302441.3, ENST00000304788.4
    Conserved Domains (1) summary
    cl26185
    Location:6234
    Hydrolase; haloacid dehalogenase-like hydrolase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    25612935..25624014 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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