Format

Send to:

Choose Destination

TMEM37 transmembrane protein 37 [ Homo sapiens (human) ]

Gene ID: 140738, updated on 3-Jun-2018
Official Symbol
TMEM37provided by HGNC
Official Full Name
transmembrane protein 37provided by HGNC
Primary source
HGNC:HGNC:18216
See related
Ensembl:ENSG00000171227 Vega:OTTHUMG00000153304
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PR; PR1
Expression
Broad expression in kidney (RPKM 36.6), fat (RPKM 26.3) and 17 other tissues See more
Orthologs
See TMEM37 in Genome Data Viewer
Location:
2q14.2
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (119429912..119438520)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (120187501..120196096)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene chromosome 2 open reading frame 76 Neighboring gene diazepam binding inhibitor, acyl-CoA binding protein Neighboring gene uncharacterized LOC107105282 Neighboring gene secretin receptor Neighboring gene VISTA enhancer hs1941 Neighboring gene cilia and flagella associated protein 221

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat 47-59 peptide downregulates gene expression of transmembrane protein 37 (TMEM37) in U-937 macrophages PubMed

Go to the HIV-1, Human Interaction Database

  • MAPK Signaling Pathway, organism-specific biosystem (from WikiPathways)
    MAPK Signaling Pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium channel activity IEA
Inferred from Electronic Annotation
more info
 
voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
voltage-dependent calcium channel gamma-like subunit
Names
neuronal voltage-gated calcium channel gamma-like subunit
voltage-dependent calcium channel gamma subunit-like protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183240.2NP_899063.2  voltage-dependent calcium channel gamma-like subunit

    See identical proteins and their annotated locations for NP_899063.2

    Status: VALIDATED

    Source sequence(s)
    AC013275, DR003856, DR005637
    Consensus CDS
    CCDS33281.1
    UniProtKB/Swiss-Prot
    Q8WXS4
    Related
    ENSP00000303148.4, OTTHUMP00000203651, ENST00000306406.4, OTTHUMT00000330638
    Conserved Domains (1) summary
    pfam15108
    Location:8187
    TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    119429912..119438520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510659.2XP_011508961.1  voltage-dependent calcium channel gamma-like subunit isoform X1

    UniProtKB/TrEMBL
    E7EMC0
    Related
    ENSP00000387015.1, OTTHUMP00000203653, ENST00000409826.1, OTTHUMT00000330640
    Conserved Domains (1) summary
    pfam15108
    Location:20199
    TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family
  2. XM_005263598.4XP_005263655.1  voltage-dependent calcium channel gamma-like subunit isoform X2

    See identical proteins and their annotated locations for XP_005263655.1

    UniProtKB/TrEMBL
    Q86SV2
    Conserved Domains (1) summary
    pfam15108
    Location:1100
    TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family
  3. XM_006712300.3XP_006712363.1  voltage-dependent calcium channel gamma-like subunit isoform X2

    See identical proteins and their annotated locations for XP_006712363.1

    UniProtKB/TrEMBL
    Q86SV2
    Conserved Domains (1) summary
    pfam15108
    Location:1100
    TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family
Support Center