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UBLCP1 ubiquitin like domain containing CTD phosphatase 1 [ Homo sapiens (human) ]

Gene ID: 134510, updated on 7-Jun-2020

Summary

Official Symbol
UBLCP1provided by HGNC
Official Full Name
ubiquitin like domain containing CTD phosphatase 1provided by HGNC
Primary source
HGNC:HGNC:28110
See related
Ensembl:ENSG00000164332 MIM:609867
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CPUB1
Expression
Ubiquitous expression in testis (RPKM 19.2), brain (RPKM 17.4) and 25 other tissues See more
Orthologs

Genomic context

See UBLCP1 in Genome Data Viewer
Location:
5q33.3
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (159263290..159286036)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (158690089..158713048)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ring finger protein 145 Neighboring gene uncharacterized LOC107986468 Neighboring gene long intergenic non-protein coding RNA 1932 Neighboring gene uncharacterized LOC105377683 Neighboring gene RNA, U4atac small nuclear 2, pseudogene Neighboring gene interleukin 12B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25267, MGC10067

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
protein dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ubiquitin-like domain-containing CTD phosphatase 1
Names
CTD phosphatase-like with ubiquitin domain 1
CTD-like phosphatase domain-containing protein
nuclear proteasome inhibitor UBLCP1
NP_659486.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145049.5NP_659486.2  ubiquitin-like domain-containing CTD phosphatase 1

    See identical proteins and their annotated locations for NP_659486.2

    Status: VALIDATED

    Source sequence(s)
    AC011418, AY444562, DA930581
    Consensus CDS
    CCDS4345.1
    UniProtKB/Swiss-Prot
    Q8WVY7
    Related
    ENSP00000296786.6, ENST00000296786.8
    Conserved Domains (2) summary
    TIGR02245
    Location:117311
    HAD_IIID1; HAD-superfamily subfamily IIID hydrolase, TIGR02245
    cd01813
    Location:377
    UBP_N; UBP ubiquitin processing protease

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    159263290..159286036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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