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Crem cAMP responsive element modulator [ Mus musculus (house mouse) ]

Gene ID: 12916, updated on 23-Apr-2024

Summary

Official Symbol
Cremprovided by MGI
Official Full Name
cAMP responsive element modulatorprovided by MGI
Primary source
MGI:MGI:88495
See related
Ensembl:ENSMUSG00000063889 AllianceGenome:MGI:88495
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ICER; ICERI
Summary
This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]
Expression
Biased expression in testis adult (RPKM 21.9), liver adult (RPKM 1.8) and 9 other tissues See more
Orthologs
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Genomic context

Location:
18 A1; 18 2.14 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (3263181..3337688, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (3266354..3337773, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor, pseudogene 152 Neighboring gene STARR-seq mESC enhancer starr_43652 Neighboring gene STARR-seq mESC enhancer starr_43653 Neighboring gene vomeronasal 1 receptor, 238 Neighboring gene STARR-seq mESC enhancer starr_43654 Neighboring gene STARR-seq mESC enhancer starr_43655 Neighboring gene STARR-positive B cell enhancer ABC_E5646 Neighboring gene predicted gene 6225 Neighboring gene cullin 2 Neighboring gene profilin 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (5) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of ATF4-CREB1 transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cAMP-responsive element modulator
Names
cAMP responsive element moderator
inducible cAMP early repressor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110850.2NP_001104320.1  cAMP-responsive element modulator isoform 4

    See identical proteins and their annotated locations for NP_001104320.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4, also known as alpha gamma) lacks three alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AY738716, BP770366, BQ556287
    UniProtKB/TrEMBL
    F6U9F5
    Related
    ENSMUSP00000115336.2, ENSMUST00000137568.8
    Conserved Domains (2) summary
    cd14690
    Location:177231
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  2. NM_001110851.1NP_001104321.1  cAMP-responsive element modulator isoform 7

    See identical proteins and their annotated locations for NP_001104321.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) contains multiple differences in the UTRs and coding region, including a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (7) contains a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AK009841, AK010806, AK161366
    Consensus CDS
    CCDS50213.1
    UniProtKB/TrEMBL
    Q3TTH6
    Related
    ENSMUSP00000122282.2, ENSMUST00000142690.2
    Conserved Domains (1) summary
    pfam02173
    Location:96135
    pKID; pKID domain
  3. NM_001110852.1NP_001104322.1  cAMP-responsive element modulator isoform 8

    See identical proteins and their annotated locations for NP_001104322.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) contains multiple differences in the UTRs and coding region, including a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (8) contains a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AK010806
    Consensus CDS
    CCDS50212.1
    UniProtKB/TrEMBL
    Q9CQ87
    Related
    ENSMUSP00000121210.2, ENSMUST00000149803.8
    Conserved Domains (1) summary
    pfam02173
    Location:4786
    pKID; pKID domain
  4. NM_001110853.2NP_001104323.1  cAMP-responsive element modulator isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5'UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (9) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK015641, AK076797, BP770366, BQ556287
    Consensus CDS
    CCDS50211.1
    UniProtKB/TrEMBL
    E9PV35, F6XRJ7
    Related
    ENSMUSP00000121118.2, ENSMUST00000122958.8
    Conserved Domains (2) summary
    cd14690
    Location:248302
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:5998
    pKID; pKID domain
  5. NM_001110854.1NP_001104324.2  cAMP-responsive element modulator isoform 10

    See identical proteins and their annotated locations for NP_001104324.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) contains multiple differences in the UTRs and coding region, including lacking multiple exons, compared to variant 1. It represents use of an alternate promoter and contains an alternate 5' coding region. The encoded isoform (10) is shorter and has distinct N- and C- termini, compared to isoform 1.
    Source sequence(s)
    AJ311667, AY738716, BE689077, BP770366, BQ556287
    Consensus CDS
    CCDS50210.2
    UniProtKB/TrEMBL
    F6QWT6, Q78Z98
    Related
    ENSMUSP00000119194.3, ENSMUST00000154705.8
    Conserved Domains (1) summary
    cd14690
    Location:69123
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  6. NM_001110855.1NP_001104325.2  cAMP-responsive element modulator isoform 11

    See identical proteins and their annotated locations for NP_001104325.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) contains multiple differences in the UTRs and coding region, including lacking multiple exons, compared to variant 1. It represents use of an alternate promoter and contains an alternate 5' coding region. The encoded isoform (11) is shorter and has distinct N- and C- termini, compared to isoform 1.
    Source sequence(s)
    AJ292222, AY738716, BE689077, BP770366, BQ556287
    Consensus CDS
    CCDS50209.2
    UniProtKB/TrEMBL
    F6VJ22, Q78Z98
    Related
    ENSMUSP00000118578.3, ENSMUST00000151084.8
    Conserved Domains (1) summary
    cd14690
    Location:57111
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  7. NM_001110856.2NP_001104326.1  cAMP-responsive element modulator isoform 2

    See identical proteins and their annotated locations for NP_001104326.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2, also known as epsilon or tau 1 alpha) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AY738718, BP770366, BQ556287
    Consensus CDS
    CCDS50214.1
    UniProtKB/TrEMBL
    F6Q346
    Related
    ENSMUSP00000119353.2, ENSMUST00000131899.8
    Conserved Domains (2) summary
    cd14690
    Location:238292
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  8. NM_001110857.2NP_001104327.1  cAMP-responsive element modulator isoform 5

    See identical proteins and their annotated locations for NP_001104327.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5, also known as beta) lacks two alternate in-frame exons, compared to variant 1. The structure of this variant is characterized in PMID: 1847666. The encoded isoform (5) is shorter than isoform 1.
    Source sequence(s)
    AC117589
    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:189243
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  9. NM_001110858.2NP_001104328.1  cAMP-responsive element modulator isoform 6

    See identical proteins and their annotated locations for NP_001104328.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6, also known as gamma) lacks three alternate in-frame exons, compared to variant 1. The structure of this variant is characterized in PMID: 1847666. The encoded isoform (6) is shorter than isoform 1.
    Source sequence(s)
    AC117589
    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:177231
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  10. NM_001110859.2NP_001104329.1  cAMP-responsive element modulator isoform 1

    See identical proteins and their annotated locations for NP_001104329.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1, also known as tau) encodes the longest isoform (1). The structure of this variant is described in PMID: 1370576.
    Source sequence(s)
    AC117589
    Consensus CDS
    CCDS50215.1
    UniProtKB/Swiss-Prot
    P27698, P27699, Q5XTP8, Q5XTP9, Q5XTQ0, Q5XTQ1, Q5XTQ2, Q5XTQ3, Q99JF1
    UniProtKB/TrEMBL
    F6XRJ7
    Conserved Domains (2) summary
    cd14690
    Location:301355
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  11. NM_001271503.1NP_001258432.1  cAMP-responsive element modulator isoform 12

    See identical proteins and their annotated locations for NP_001258432.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12, also known as tau 1 gamma) lacks two alternate in-frame exons, compared to variant 1. The encoded isoform (12) is shorter than isoform 1.
    Source sequence(s)
    AC117589, AY738715
    UniProtKB/TrEMBL
    F6RB97
    Related
    ENSMUSP00000119638.2, ENSMUST00000146265.8
    Conserved Domains (2) summary
    cd14690
    Location:226280
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  12. NM_001271504.1NP_001258433.1  cAMP-responsive element modulator isoform 13

    See identical proteins and their annotated locations for NP_001258433.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13, also known as tau 1 alpha gamma) lacks two alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (13) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AY738717
    Consensus CDS
    CCDS70863.1
    UniProtKB/TrEMBL
    F6Q346
    Conserved Domains (2) summary
    cd14690
    Location:226280
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  13. NM_001271505.1NP_001258434.1  cAMP-responsive element modulator isoform 14

    See identical proteins and their annotated locations for NP_001258434.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14, also known as tau 2 alpha) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (14) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AY738719
    Consensus CDS
    CCDS70862.1
    UniProtKB/TrEMBL
    F6W4F5
    Related
    ENSMUSP00000123515.2, ENSMUST00000152900.8
    Conserved Domains (2) summary
    cd14690
    Location:252306
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  14. NM_001271506.1NP_001258435.1  cAMP-responsive element modulator isoform 15

    See identical proteins and their annotated locations for NP_001258435.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15, also known as tau alpha gamma) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (15) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589, AY738721
    Consensus CDS
    CCDS70864.1
    UniProtKB/TrEMBL
    F6QKL8
    Related
    ENSMUSP00000121541.2, ENSMUST00000130455.8
    Conserved Domains (2) summary
    cd14690
    Location:289343
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  15. NM_001311066.1NP_001297995.1  cAMP-responsive element modulator isoform 16

    See identical proteins and their annotated locations for NP_001297995.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) lacks part of the 5' coding region, uses an alternate 5'-terminal exon and a downstream in-frame start codon, compared to variant 1. The encoded isoform (16) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC117589, AK076797, BP770366, BP771675, CX217456
    Consensus CDS
    CCDS79584.1
    UniProtKB/TrEMBL
    D3Z326, Q78Z98
    Related
    ENSMUSP00000121352.2, ENSMUST00000124747.8
    Conserved Domains (1) summary
    cd14690
    Location:46100
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  16. NM_001311067.1NP_001297996.1  cAMP-responsive element modulator isoform 17

    See identical proteins and their annotated locations for NP_001297996.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) lacks part of the 5' coding region, uses an alternate 5'-terminal exon and an alternate start codon, compared to variant 1. The encoded isoform (17) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC117589
    Consensus CDS
    CCDS79585.1
    UniProtKB/TrEMBL
    D3Z6A5, Q78Z98
    Related
    ENSMUSP00000061925.7, ENSMUST00000049942.13
    Conserved Domains (1) summary
    cd14690
    Location:63117
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  17. NM_001374833.1NP_001361762.1  cAMP-responsive element modulator isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC117589
    Consensus CDS
    CCDS89179.1
    UniProtKB/TrEMBL
    D3Z2U7, F6QKL8
    Related
    ENSMUSP00000121388.2, ENSMUST00000156234.8
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  18. NM_013498.3NP_038526.2  cAMP-responsive element modulator isoform 3

    See identical proteins and their annotated locations for NP_038526.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3, also known as alpha) lacks two alternate in-frame exons and uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC117589
    Consensus CDS
    CCDS29031.2
    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:189243
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain

RNA

  1. NR_073193.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) contains multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC117589, AY738720

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    3263181..3337688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525570.3XP_006525633.1  cAMP-responsive element modulator isoform X23

    UniProtKB/TrEMBL
    D3Z011, D3Z0R0
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3574
    pKID; pKID domain
  2. XM_030250301.2XP_030106161.1  cAMP-responsive element modulator isoform X9

    UniProtKB/TrEMBL
    D3Z0R0
    Conserved Domains (2) summary
    cd14690
    Location:261315
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:84123
    pKID; pKID domain
  3. XM_030250300.2XP_030106160.1  cAMP-responsive element modulator isoform X7

    UniProtKB/TrEMBL
    D3Z0R0
    Conserved Domains (2) summary
    cd14690
    Location:273327
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:84123
    pKID; pKID domain
  4. XM_030250303.2XP_030106163.1  cAMP-responsive element modulator isoform X18

    UniProtKB/TrEMBL
    F6XRJ7
    Conserved Domains (2) summary
    cd14690
    Location:236290
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:5998
    pKID; pKID domain
  5. XM_006525579.4XP_006525642.1  cAMP-responsive element modulator isoform X39

    See identical proteins and their annotated locations for XP_006525642.1

    UniProtKB/TrEMBL
    D3YVP3
    Related
    ENSMUSP00000114280.2, ENSMUST00000147138.8
    Conserved Domains (1) summary
    cd14690
    Location:69123
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  6. XM_006525580.4XP_006525643.1  cAMP-responsive element modulator isoform X40

    See identical proteins and their annotated locations for XP_006525643.1

    UniProtKB/TrEMBL
    D3YVP3
    Related
    ENSMUSP00000115423.2, ENSMUST00000140332.8
    Conserved Domains (1) summary
    cd14690
    Location:57111
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  7. XM_030250313.2XP_030106173.1  cAMP-responsive element modulator isoform X41

    UniProtKB/TrEMBL
    D3YVP3
    Conserved Domains (1) summary
    cd14690
    Location:46100
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  8. XM_030250306.2XP_030106166.1  cAMP-responsive element modulator isoform X27

    UniProtKB/TrEMBL
    F6RB97
    Conserved Domains (2) summary
    cd14690
    Location:222276
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  9. XM_036160962.1XP_036016855.1  cAMP-responsive element modulator isoform X19

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:236290
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  10. XM_036160968.1XP_036016861.1  cAMP-responsive element modulator isoform X37

    UniProtKB/TrEMBL
    A0A0R4J1V7, F6U9F5
    Related
    ENSMUSP00000120557.2, ENSMUST00000123672.8
    Conserved Domains (2) summary
    cd14690
    Location:161215
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  11. XM_036160959.1XP_036016852.1  cAMP-responsive element modulator isoform X5

    UniProtKB/TrEMBL
    F6XRJ7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  12. XM_006525565.5XP_006525628.1  cAMP-responsive element modulator isoform X15

    See identical proteins and their annotated locations for XP_006525628.1

    UniProtKB/TrEMBL
    F6Q346
    Related
    ENSMUSP00000127353.2, ENSMUST00000165086.8
    Conserved Domains (2) summary
    cd14690
    Location:238292
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  13. XM_036160966.1XP_036016859.1  cAMP-responsive element modulator isoform X26

    UniProtKB/TrEMBL
    F6Q346
    Conserved Domains (2) summary
    cd14690
    Location:222276
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  14. XM_030250309.2XP_030106169.1  cAMP-responsive element modulator isoform X34

    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:173227
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  15. XM_030250308.1XP_030106168.1  cAMP-responsive element modulator isoform X28

    UniProtKB/TrEMBL
    F6Q346
    Conserved Domains (2) summary
    cd14690
    Location:210264
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  16. XM_036160967.1XP_036016860.1  cAMP-responsive element modulator isoform X29

    UniProtKB/TrEMBL
    F6RB97
    Conserved Domains (2) summary
    cd14690
    Location:210264
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  17. XM_036160960.1XP_036016853.1  cAMP-responsive element modulator isoform X8

    UniProtKB/TrEMBL
    F6QKL8
    Conserved Domains (2) summary
    cd14690
    Location:273327
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:96135
    pKID; pKID domain
  18. XM_006525561.5XP_006525624.1  cAMP-responsive element modulator isoform X10

    See identical proteins and their annotated locations for XP_006525624.1

    UniProtKB/TrEMBL
    F6W4F5
    Related
    ENSMUSP00000080780.6, ENSMUST00000082141.12
    Conserved Domains (2) summary
    cd14690
    Location:252306
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  19. XM_030250311.1XP_030106171.1  cAMP-responsive element modulator isoform X36

    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:161215
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  20. XM_030250305.1XP_030106165.1  cAMP-responsive element modulator isoform X24

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  21. XM_036160965.1XP_036016858.1  cAMP-responsive element modulator isoform X25

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  22. XM_006525566.5XP_006525629.1  cAMP-responsive element modulator isoform X17

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:236290
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  23. XM_036160969.1XP_036016862.1  cAMP-responsive element modulator isoform X38

    UniProtKB/TrEMBL
    D3Z773
    Conserved Domains (2) summary
    cd14690
    Location:149203
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3574
    pKID; pKID domain
  24. XM_030250310.2XP_030106170.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A0R4J1S0, F6U9F5
    Related
    ENSMUSP00000115471.2, ENSMUST00000130599.8
    Conserved Domains (2) summary
    cd14690
    Location:173227
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:4786
    pKID; pKID domain
  25. XM_030250302.1XP_030106162.1  cAMP-responsive element modulator isoform X11

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:252306
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  26. XM_036160964.1XP_036016857.1  cAMP-responsive element modulator isoform X23

    UniProtKB/TrEMBL
    D3Z011, D3Z0R0
    Related
    ENSMUSP00000120349.2, ENSMUST00000144496.8
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3574
    pKID; pKID domain
  27. XM_036160963.1XP_036016856.1  cAMP-responsive element modulator isoform X22

    UniProtKB/TrEMBL
    D3Z0R0
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3574
    pKID; pKID domain
  28. XM_006525576.4XP_006525639.1  cAMP-responsive element modulator isoform X33

    See identical proteins and their annotated locations for XP_006525639.1

    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:177231
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  29. XM_006525575.4XP_006525638.1  cAMP-responsive element modulator isoform X32

    See identical proteins and their annotated locations for XP_006525638.1

    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:177231
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  30. XM_006525574.4XP_006525637.1  cAMP-responsive element modulator isoform X31

    See identical proteins and their annotated locations for XP_006525637.1

    UniProtKB/TrEMBL
    F6U9F5
    Conserved Domains (2) summary
    cd14690
    Location:189243
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  31. XM_006525573.4XP_006525636.1  cAMP-responsive element modulator isoform X30

    See identical proteins and their annotated locations for XP_006525636.1

    UniProtKB/TrEMBL
    F6U9F5
    Related
    ENSMUSP00000122051.2, ENSMUST00000154135.8
    Conserved Domains (2) summary
    cd14690
    Location:189243
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  32. XM_006525564.4XP_006525627.1  cAMP-responsive element modulator isoform X14

    UniProtKB/TrEMBL
    D3YXV5, F6W4F5
    Related
    ENSMUSP00000118267.2, ENSMUST00000151311.8
    Conserved Domains (2) summary
    cd14690
    Location:240294
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  33. XM_006525563.4XP_006525626.1  cAMP-responsive element modulator isoform X13

    UniProtKB/TrEMBL
    F6W4F5
    Conserved Domains (2) summary
    cd14690
    Location:240294
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:63102
    pKID; pKID domain
  34. XM_006525567.4XP_006525630.1  cAMP-responsive element modulator isoform X20

    See identical proteins and their annotated locations for XP_006525630.1

    UniProtKB/TrEMBL
    F6Q346
    Related
    ENSMUSP00000118128.2, ENSMUST00000154470.8
    Conserved Domains (2) summary
    cd14690
    Location:226280
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  35. XM_017317808.2XP_017173297.1  cAMP-responsive element modulator isoform X16

    UniProtKB/TrEMBL
    F6RB97
    Conserved Domains (2) summary
    cd14690
    Location:238292
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  36. XM_006525557.4XP_006525620.1  cAMP-responsive element modulator isoform X4

    UniProtKB/TrEMBL
    F6XRJ7
    Related
    ENSMUSP00000118649.2, ENSMUST00000127601.8
    Conserved Domains (2) summary
    cd14690
    Location:289343
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  37. XM_006525556.4XP_006525619.1  cAMP-responsive element modulator isoform X3

    See identical proteins and their annotated locations for XP_006525619.1

    UniProtKB/TrEMBL
    F6QKL8
    Related
    ENSMUSP00000025069.5, ENSMUST00000025069.11
    Conserved Domains (2) summary
    cd14690
    Location:289343
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  38. XM_006525554.4XP_006525617.1  cAMP-responsive element modulator isoform X1

    See identical proteins and their annotated locations for XP_006525617.1

    UniProtKB/TrEMBL
    F6QKL8
    Conserved Domains (2) summary
    cd14690
    Location:301355
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  39. XM_011246820.4XP_011245122.1  cAMP-responsive element modulator isoform X1

    See identical proteins and their annotated locations for XP_011245122.1

    UniProtKB/TrEMBL
    F6QKL8
    Conserved Domains (2) summary
    cd14690
    Location:301355
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  40. XM_006525559.2XP_006525622.1  cAMP-responsive element modulator isoform X6

    See identical proteins and their annotated locations for XP_006525622.1

    UniProtKB/TrEMBL
    D3Z7M6, F6QKL8
    Conserved Domains (2) summary
    cd14690
    Location:273327
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:84123
    pKID; pKID domain
  41. XM_006525560.1XP_006525623.1  cAMP-responsive element modulator isoform X6

    See identical proteins and their annotated locations for XP_006525623.1

    UniProtKB/TrEMBL
    D3Z7M6, F6QKL8
    Related
    ENSMUSP00000122179.2, ENSMUST00000154715.8
    Conserved Domains (2) summary
    cd14690
    Location:273327
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:84123
    pKID; pKID domain
  42. XM_006525562.5XP_006525625.1  cAMP-responsive element modulator isoform X12

    See identical proteins and their annotated locations for XP_006525625.1

    UniProtKB/TrEMBL
    E9PWV9, F6QKL8
    Related
    ENSMUSP00000114780.2, ENSMUST00000126578.8
    Conserved Domains (2) summary
    cd14690
    Location:248302
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:5998
    pKID; pKID domain
  43. XM_030250315.2XP_030106175.1  cAMP-responsive element modulator isoform X42

    UniProtKB/TrEMBL
    D3Z7P7, Q78Z98
    Related
    ENSMUSP00000122123.2, ENSMUST00000139537.2
    Conserved Domains (1) summary
    cd14690
    Location:3993
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  44. XM_006525555.5XP_006525618.1  cAMP-responsive element modulator isoform X2

    See identical proteins and their annotated locations for XP_006525618.1

    UniProtKB/Swiss-Prot
    P27698, P27699, Q5XTP8, Q5XTP9, Q5XTQ0, Q5XTQ1, Q5XTQ2, Q5XTQ3, Q99JF1
    UniProtKB/TrEMBL
    F6XRJ7
    Related
    ENSMUSP00000121233.2, ENSMUST00000150235.8
    Conserved Domains (2) summary
    cd14690
    Location:301355
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain
  45. XM_006525568.5XP_006525631.1  cAMP-responsive element modulator isoform X21

    See identical proteins and their annotated locations for XP_006525631.1

    UniProtKB/TrEMBL
    F6RB97
    Conserved Domains (2) summary
    cd14690
    Location:226280
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:112151
    pKID; pKID domain