U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Crabp1 cellular retinoic acid binding protein I [ Mus musculus (house mouse) ]

Gene ID: 12903, updated on 17-Jan-2023

Summary

Official Symbol
Crabp1provided by MGI
Official Full Name
cellular retinoic acid binding protein Iprovided by MGI
Primary source
MGI:MGI:88490
See related
Ensembl:ENSMUSG00000032291 AllianceGenome:MGI:88490
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rbp-5; CrabpI; CRABP-I; Crabp-1
Summary
Predicted to enable fatty acid binding activity and retinoic acid binding activity. Predicted to be involved in fatty acid transport. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human CRABP1 (cellular retinoic acid binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 232.5), limb E14.5 (RPKM 196.0) and 3 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Crabp1 in Genome Data Viewer
Location:
9 A5.3; 9 29.76 cM
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54672032..54680394)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54764748..54773110)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member A4 Neighboring gene microRNA 5710 Neighboring gene SKI8 subunit of superkiller complex Neighboring gene RAB7, member RAS oncogene family, pseudogene 1 Neighboring gene iron responsive element binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fatty acid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables retinal binding IEA
Inferred from Electronic Annotation
more info
 
enables retinoic acid binding ISO
Inferred from Sequence Orthology
more info
 
enables retinoid binding TAS
Traceable Author Statement
more info
PubMed 
enables retinol binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in fatty acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retinoic acid catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cellular retinoic acid-binding protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284507.1NP_001271436.1  cellular retinoic acid-binding protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001271436.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    AC159892
    Conserved Domains (1) summary
    cl10502
    Location:299
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
  2. NM_013496.3NP_038524.1  cellular retinoic acid-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_038524.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC159892, AK144397, CD742428
    Consensus CDS
    CCDS23195.1
    UniProtKB/Swiss-Prot
    P62965, Q3UN78
    UniProtKB/TrEMBL
    A0A6P5Q7E9, A0A8C6GDH6
    Related
    ENSMUSP00000034830.9, ENSMUST00000034830.9
    Conserved Domains (1) summary
    cd19460
    Location:2137
    CRABP1; cellular retinoic acid-binding protein 1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    54672032..54680394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)