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SLX4IP SLX4 interacting protein [ Homo sapiens (human) ]

Gene ID: 128710, updated on 28-Nov-2021

Summary

Official Symbol
SLX4IPprovided by HGNC
Official Full Name
SLX4 interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:16225
See related
Ensembl:ENSG00000149346 MIM:615958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf94; bA204H22.1; bA254M13.1; dJ1099D15.3
Expression
Ubiquitous expression in skin (RPKM 1.0), testis (RPKM 0.9) and 25 other tissues See more
Orthologs
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Genomic context

See SLX4IP in Genome Data Viewer
Location:
20p12.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (10435136..10628138)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (10415953..10608678)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene SDA1 domain containing 1 pseudogene 2 Neighboring gene MKKS centrosomal shuttling protein Neighboring gene Sharpr-MPRA regulatory region 2397 Neighboring gene Sharpr-MPRA regulatory region 8388 Neighboring gene Sharpr-MPRA regulatory region 11569 Neighboring gene DnaJ heat shock protein family (Hsp40) member C9 pseudogene Neighboring gene microRNA 6870 Neighboring gene jagged canonical Notch ligand 1 Neighboring gene long intergenic non-protein coding RNA 1752

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr interacts with TSPYL1 and C20orf94 subunits of the SLX4 complex in Vpr-expressing THP-1 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009608.3NP_001009608.1  protein SLX4IP

    See identical proteins and their annotated locations for NP_001009608.1

    Status: VALIDATED

    Source sequence(s)
    AL035456, BC026094, CA416447
    Consensus CDS
    CCDS33439.1
    UniProtKB/Swiss-Prot
    Q5VYV7
    Related
    ENSP00000335557.5, ENST00000334534.10
    Conserved Domains (1) summary
    pfam15744
    Location:10366
    UPF0492; Uncharacterized protein family UPF0492

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    10435136..10628138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451828.1XP_024307596.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  2. XM_024451827.1XP_024307595.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  3. XM_024451829.1XP_024307597.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  4. XM_024451831.1XP_024307599.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  5. XM_024451830.1XP_024307598.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  6. XM_017027647.2XP_016883136.1  protein SLX4IP isoform X3

  7. XM_017027651.2XP_016883140.1  protein SLX4IP isoform X1

    Conserved Domains (1) summary
    pfam15744
    Location:53350
    UPF0492; Uncharacterized protein family UPF0492
  8. XM_024451832.1XP_024307600.1  protein SLX4IP isoform X2

    Conserved Domains (1) summary
    pfam15744
    Location:5201
    UPF0492; Uncharacterized protein family UPF0492
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