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Cox6c cytochrome c oxidase subunit 6C [ Mus musculus (house mouse) ]

Gene ID: 12864, updated on 5-Jan-2022


Official Symbol
Cox6cprovided by MGI
Official Full Name
cytochrome c oxidase subunit 6Cprovided by MGI
Primary source
See related
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Predicted to enable cytochrome-c oxidase activity. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human COX6C (cytochrome c oxidase subunit 6C). [provided by Alliance of Genome Resources, Nov 2021]
Ubiquitous expression in heart adult (RPKM 387.4), bladder adult (RPKM 339.2) and 28 other tissues See more
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Genomic context

See Cox6c in Genome Data Viewer
15; 15 B3.1
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (35932122..35938392, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (35931976..35938246, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (35861731..35868001, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 13B Neighboring gene RIKEN cDNA 9130002K18 gene Neighboring gene predicted gene, 41292 Neighboring gene regulator of G-protein signalling 22 Neighboring gene heterogeneous nuclear ribonucleoprotein C pseudogene Neighboring gene predicted gene, 22979 Neighboring gene F-box protein 43

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytochrome-c oxidase activity IEA
Inferred from Electronic Annotation
more info
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
part_of mitochondrial respiratory chain complex IV ISO
Inferred from Sequence Orthology
more info
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
cytochrome c oxidase subunit 6C
cytochrome c oxidase polypeptide VIc
cytochrome c oxidase subunit VIc

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053071.2NP_444301.1  cytochrome c oxidase subunit 6C

    See identical proteins and their annotated locations for NP_444301.1

    Status: VALIDATED

    Source sequence(s)
    AK013459, BC094413, BY100624
    Consensus CDS
    ENSMUSP00000014457.9, ENSMUST00000014457.15
    Conserved Domains (1) summary
    COX6C; Cytochrome c oxidase subunit VIc

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000081.7 Reference GRCm39 C57BL/6J

    35932122..35938392 complement
    GenBank, FASTA, Sequence Viewer (Graphics)
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