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Cd3g CD3 antigen, gamma polypeptide [ Mus musculus (house mouse) ]

Gene ID: 12502, updated on 23-Jun-2021

Summary

Official Symbol
Cd3gprovided by MGI
Official Full Name
CD3 antigen, gamma polypeptideprovided by MGI
Primary source
MGI:MGI:88333
See related
Ensembl:ENSMUSG00000002033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
T3g; Ctg3; Ctg-3
Expression
Biased expression in thymus adult (RPKM 54.5), spleen adult (RPKM 5.5) and 2 other tissues See more
Orthologs
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Genomic context

See Cd3g in Genome Data Viewer
Location:
9 A5.2; 9 24.84 cM
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44880870..44891729, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44969572..44980431, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (44777655..44788514, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G Neighboring gene predicted gene, 30934 Neighboring gene ubiquitination factor E4A Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class A pseudogene Neighboring gene CD3 antigen, delta polypeptide Neighboring gene CD3 antigen, epsilon polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment or maintenance of cell polarity ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive thymic T cell selection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein transport ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of lymphocyte apoptotic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of alpha-beta T cell receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of alpha-beta T cell receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of alpha-beta T cell receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
T-cell surface glycoprotein CD3 gamma chain
Names
T-cell receptor T3 gamma chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009850.2NP_033980.1  T-cell surface glycoprotein CD3 gamma chain precursor

    See identical proteins and their annotated locations for NP_033980.1

    Status: VALIDATED

    Source sequence(s)
    AC061963, BC027528, BY224047
    Consensus CDS
    CCDS23123.1
    UniProtKB/Swiss-Prot
    P11942
    UniProtKB/TrEMBL
    Q3U4Y3
    Related
    ENSMUSP00000002101.6, ENSMUST00000002101.12
    Conserved Domains (2) summary
    pfam02189
    Location:157176
    ITAM; Immunoreceptor tyrosine-based activation motif
    pfam16680
    Location:40106
    Ig_4; T-cell surface glycoprotein CD3 delta chain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    44880870..44891729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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