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HSF5 heat shock transcription factor 5 [ Homo sapiens (human) ]

Gene ID: 124535, updated on 2-Oct-2018

Summary

Official Symbol
HSF5provided by HGNC
Official Full Name
heat shock transcription factor 5provided by HGNC
Primary source
HGNC:HGNC:26862
See related
Ensembl:ENSG00000176160 Vega:OTTHUMG00000179078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSF 5; HSTF 5
Expression
Restricted expression toward testis (RPKM 33.9) See more
Orthologs

Genomic context

See HSF5 in Genome Data Viewer
Location:
17q22
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 17 NC_000017.11 (58420167..58488401, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (56497528..56565759, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene TSPOAP1, SUPT4H1 and RNF43 antisense RNA 1 Neighboring gene SPT4 homolog, DSIF elongation factor subunit Neighboring gene ring finger protein 43 Neighboring gene SET pseudogene 3 Neighboring gene myotubularin related protein 4 Neighboring gene SEPT4 antisense RNA 1 Neighboring gene septin 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40311, MGC134827

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter in response to heat stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heat shock factor protein 5
Names
heat shock transcription factor family member 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080439.2NP_001073908.2  heat shock factor protein 5

    See identical proteins and their annotated locations for NP_001073908.2

    Status: VALIDATED

    Source sequence(s)
    BC033017, BI459434
    Consensus CDS
    CCDS32690.1
    UniProtKB/Swiss-Prot
    Q4G112
    Related
    ENSP00000313243.3, OTTHUMP00000260665, ENST00000323777.7, OTTHUMT00000444719
    Conserved Domains (1) summary
    pfam00447
    Location:20129
    HSF_DNA-bind; HSF-type DNA-binding

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p12 Primary Assembly

    Range
    58420167..58488401 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524283.1XP_011522585.1  heat shock factor protein 5 isoform X1

    Conserved Domains (1) summary
    pfam00447
    Location:20129
    HSF_DNA-bind; HSF-type DNA-binding
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